Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.50 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.49 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.47 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.47 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.47 |
| ▸ | XDH | P47989 | 1/20 | 0.47 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.43 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.43 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL196765 | 0.73 | CYP3A4 (0.73) | DYRK1ACLK4GAANOTUMXDH | |
| SCHEMBL29489425 | 0.73 | CYP3A4 (0.73) | DYRK1ACLK4GAANOTUMXDH | |
| Ammonia Solution, Strong SCHEMBL27960505 | 0.71 | CYP3A4 (0.70) | DYRK1ACLK4GAANOTUMXDH | |
| SCHEMBL29628977 | 0.71 | CYP3A4 (0.77) | DYRK1ACLK4GAANOTUMXDH | |
| Hydrogen Sulfide SCHEMBL28640169 | 0.71 | CYP3A4 (0.70) | DYRK1ACLK4GAANOTUMXDH | |
| SCHEMBL703677 | 0.70 | DCUN1D1 (0.54) | DCUN1D1DYRK1ACLK4GAANOTUM | |
| SCHEMBL1180343 | 0.69 | ABL1 (0.69) | DYRK1ACLK4XDHCYP1A2CYP2C9 | |
| SCHEMBL4720179 | 0.69 | ALDH1A1 (0.50) | DCUN1D1GAAXDHMAPTSMN1; SMN2 | |
| SCHEMBL4053635 | 0.69 | GAA (0.50) | DCUN1D1DYRK1ACLK4GAANOTUM | |
| SCHEMBL4041229 | 0.69 | DCUN1D1 (0.52) | DCUN1D1DYRK1ACLK4GAANOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2056844-A2 | NOVEL MACROLIDES AND KETOLIDES HAVING ANTIMICROBIAL ACTIVITY | Wockhardt Research Centre (IN) | 2009-05-13 | — | — | EP | claimed |
| WO-2008023248-A2 | NOVEL MACROLIDES AND KETOLIDES HAVING ANTIMICROBIAL ACTIVITY | WOCKHARDT RESEARCH CENTRE (IN) | 2008-02-28 | — | — | WO | claimed |