Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 18/20 | 0.44 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
| ▸ | IKZF2 | Q9UKS7 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3590379 | 0.92 | TRPV1 (0.43) | TRPV1CSNK1A1CRBNIKZF2MEN1 | |
| SCHEMBL3590382 | 0.92 | TRPV1 (0.43) | TRPV1CSNK1A1CRBNIKZF2MEN1 | |
| SCHEMBL3590842 | 0.87 | TRPV1 (0.41) | TRPV1CSNK1A1CRBNIKZF2MEN1 | |
| SCHEMBL3590846 | 0.87 | TRPV1 (0.41) | TRPV1CSNK1A1CRBNIKZF2MEN1 | |
| SCHEMBL1450532 | 0.86 | TRPV1 (0.49) | TRPV1CSNK1A1CRBNIKZF2 | |
| SCHEMBL1450537 | 0.86 | TRPV1 (0.49) | TRPV1CSNK1A1CRBNIKZF2 | |
| SCHEMBL1450825 | 0.86 | TRPV1 (0.59) | TRPV1CSNK1A1CRBNIKZF2 | |
| SCHEMBL1451875 | 0.84 | TRPV1 (0.52) | TRPV1CSNK1A1CRBNIKZF2 | |
| SCHEMBL1451871 | 0.84 | TRPV1 (0.52) | TRPV1CSNK1A1CRBNIKZF2 | |
| SCHEMBL1450631 | 0.83 | TRPV1 (0.47) | TRPV1MEN1KMT2ARXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2128157-A1 | HETEROCYCLIDENE-N-(ARYL)ACETAMIDE DERIVATIVE | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2009-12-02 | — | — | EP | disclosed |