SCHEMBL1450532

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1450537	1.00	TRPV1 (0.49)	TRPV1PYGLPIRGSK3BHSF1
	SCHEMBL1450825	0.88	TRPV1 (0.59)	TRPV1CSNK1A1CRBNIKZF2
	SCHEMBL4447940	0.86	TRPV1 (0.44)	TRPV1CSNK1A1CRBNIKZF2
	SCHEMBL3590382	0.85	TRPV1 (0.43)	TRPV1CSNK1A1CRBNIKZF2
	SCHEMBL3590379	0.85	TRPV1 (0.43)	TRPV1CSNK1A1CRBNIKZF2
	SCHEMBL3584549	0.85	TRPV1 (0.47)	TRPV1CSNK1A1CRBNIKZF2
	SCHEMBL1451875	0.85	TRPV1 (0.52)	TRPV1CSNK1A1CRBNIKZF2
	SCHEMBL1451871	0.85	TRPV1 (0.52)	TRPV1CSNK1A1CRBNIKZF2
	SCHEMBL1451423	0.85	PARP10 (0.49)	TRPV1ROCK2CSNK1A1CRBNIKZF2
	SCHEMBL1450627	0.85	TRPV1 (0.47)	TRPV1ROCK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.