Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CETP | P11597 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 3/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | MC4R | P32245 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3592600 | 1.00 | HTT (0.38) | HTTMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL15181797 | 0.91 | HTT (0.39) | HTTMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL15181817 | 0.90 | HTT (0.39) | HTTMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL3598463 | 0.89 | HTT (0.41) | HTTMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL3591231 | 0.89 | HTT (0.41) | HTTMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL4439759 | 0.89 | HTT (0.41) | HTTMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL3585646 | 0.88 | HTT (0.37) | HTTMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL3586449 | 0.88 | HTT (0.37) | HTTMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL4437675 | 0.88 | HTT (0.37) | HTTMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL3591435 | 0.88 | HTT (0.40) | HTTMEN1KMT2ACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121598-A2 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008076754-A2 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2008-06-26 | — | — | WO | disclosed |