Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 3/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 8/20 | 0.40 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.39 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.39 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GUSB | P08236 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | G6PD | P11413 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3996133 | 0.83 | SHBG (0.44) | SHBGCYP19A1CYP17A1TBXAS1SRD5A2 | |
| SCHEMBL6899628 | 0.83 | GRIN1 (0.53) | — | |
| SCHEMBL1418483 | 0.80 | CYP19A1 (0.44) | SHBGCYP19A1CYP17A1TBXAS1SRD5A2 | |
| SCHEMBL32677686 | 0.79 | SHBG (0.44) | SHBGCYP19A1CYP17A1 | |
| SCHEMBL32677691 | 0.79 | SHBG (0.44) | SHBGCYP19A1CYP17A1 | |
| SCHEMBL9853331 | 0.77 | SHBG (0.40) | SHBGCYP19A1CYP17A1CYP3A4 | |
| SCHEMBL7259580 | 0.77 | GRIN1 (0.40) | SHBGCYP19A1CYP17A1 | |
| SCHEMBL5494151 | 0.77 | CYP19A1 (0.48) | SHBGCYP19A1CYP17A1 | |
| SCHEMBL23155091 | 0.76 | SHBG (0.64) | SHBGCYP17A1TBXAS1SRD5A2SERPINA6 | |
| SCHEMBL13461623 | 0.76 | SHBG (0.64) | SHBGCYP17A1TBXAS1SRD5A2SERPINA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2012773-A2 | DRUGS AND USES | Hollis-Eden Pharmaceuticals Inc. (US) | 2009-01-14 | — | — | EP | disclosed |
| WO-2008039566-A2 | DRUGS AND USES | HOLLIS-EDEN PHARMACEUTICALS, INC. (US) | 2008-04-03 | — | — | WO | disclosed |