Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 15/20 | 0.52 |
| ▸ | PLA2G7 | Q13093 | 2/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | THRA | P10827 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2430923 | 0.87 | GPR119 (0.47) | GPR119PLA2G7 | |
| SCHEMBL2433621 | 0.87 | GPR119 (0.56) | GPR119THRATHRB | |
| SCHEMBL2426771 | 0.85 | GPR119 (0.73) | GPR119 | |
| SCHEMBL1576128 | 0.85 | GPR119 (0.73) | GPR119 | |
| SCHEMBL4440858 | 0.85 | GPR119 (0.46) | GPR119PLA2G7THRATHRB | |
| SCHEMBL2372010 | 0.81 | GPR119 (0.43) | GPR119 | |
| SCHEMBL2371910 | 0.80 | GPR119 (0.44) | GPR119ACACB | |
| SCHEMBL174827 | 0.80 | GPR119 (0.51) | GPR119 | |
| SCHEMBL2370813 | 0.80 | GPR119 (0.51) | GPR119 | |
| SCHEMBL25902816 | 0.78 | GPR119 (0.47) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2114933-A1 | PIPERIDINE GPCR AGONISTS | Prosidion Limited (GB) | 2009-11-11 | — | — | EP | disclosed |
| WO-2008081204-A1 | PIPERIDINE GPCR AGONISTS | PROSIDION LIMITED (GB) | 2008-07-10 | — | — | WO | disclosed |