Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.51 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.50 |
| ▸ | PLIN1 | O60240 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 2/20 | 0.50 |
| ▸ | PLIN5 | Q00G26 | 2/20 | 0.50 |
| ▸ | ABHD5 | Q8WTS1 | 2/20 | 0.50 |
| ▸ | TNKS | O95271 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4448325 | 1.00 | GLA (0.52) | GLATDP1AKR1B10AKR1B1MAPT | |
| SCHEMBL3907197 | 0.83 | TDP1 (0.49) | GLATDP1AKR1B10AKR1B1MAPT | |
| SCHEMBL3907189 | 0.83 | TDP1 (0.49) | GLATDP1AKR1B10AKR1B1MAPT | |
| SCHEMBL869266 | 0.83 | MAPT (0.64) | GLATDP1AKR1B10AKR1B1MAPT | |
| SCHEMBL869265 | 0.83 | MAPT (0.64) | GLATDP1AKR1B10AKR1B1MAPT | |
| SCHEMBL4448328 | 0.82 | GLA (0.55) | GLATDP1AKR1B10AKR1B1MAPT | |
| SCHEMBL7715603 | 0.82 | GLA (0.55) | GLATDP1AKR1B10AKR1B1MAPT | |
| SCHEMBL320924 | 0.80 | TDP1 (0.57) | GLATDP1AKR1B10AKR1B1MAPT | |
| SCHEMBL320925 | 0.80 | TDP1 (0.57) | GLATDP1AKR1B10AKR1B1MAPT | |
| SCHEMBL15950322 | 0.80 | MAPT (0.59) | GLATDP1AKR1B10AKR1B1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240315950-A1 | ORGANOPOLYSILOXANE AND COSMETIC CONTAINING SAME | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2024-09-26 | — | — | US | disclosed |
| EP-4293066-A1 | ORGANOPOLYSILOXANE AND COSMETIC CONTAINING SAME | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2023-12-20 | — | — | EP | disclosed |
| US-8734771-B2 | Powder treated with a power treating agent comprising an organopolysiloxane and cosmetic comprising the powder | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2014-05-27 | — | — | US | disclosed |
| EP-1829524-B1 | Powder treated with organopolysiloxane and cosmetic comprising the powder | SHINETSU CHEMICAL CO (JP) | 2013-02-20 | — | — | EP | disclosed |
| US-20090203802-A1 | POWDER COMPOSITION, A DISPERSION OF POWDER IN OIL, AND A COSMETIC COMPRISING THE SAME | KAMEI MASANAO | 2009-08-13 | — | — | US | disclosed |
| EP-1416016-B1 | Powder composition, a dispersion of powder in oil, and a cosmetic preparation comprising polyglycerine modified silicone | SHINETSU CHEMICAL CO (JP) | 2008-08-13 | — | — | EP | disclosed |
| US-20070207176-A1 | Powder treated with a power treating agent comprising an organopolysiloxane and cosmetic comprising the powder | SHIN-ETSU CHEMICAL CO., LTD. | 2007-09-06 | — | — | US | disclosed |
| EP-1829524-A2 | Organopolysiloxane powder treating agent, power treated with the agent and cosmetic comprising the powder | Shin-Etsu Chemical Co., Ltd. (JP) | 2007-09-05 | — | — | EP | disclosed |
| US-20060165629-A1 | Powder composition, a dispersion of powder in oil, and a cosmetic comprising the same | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2006-07-27 | — | — | US | disclosed |
| EP-1416016-A1 | Powder composition, a dispersion of powder in oil, and a cosmetic preparation comprising polyglycerine modified silicone | Shin-Etsu Chemical Co., Ltd. (JP) | 2004-05-06 | — | — | EP | disclosed |
| EP-0615741-B1 | Oil-in-water type emulsion composition | SHISEIDO CO LTD (JP) | 1999-07-07 | — | — | EP | disclosed |
| US-5693255-A | AMPHIPHILE AND SURFACTANT WHICH CAN FORM A GEL | SHISEIDO CO., LTD. (JP) | 1997-12-02 | — | — | US | disclosed |
| EP-0615741-A1 | Oil-in-water type emulsion composition | SHISEIDO COMPANY LIMITED (JP) | 1994-09-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060165629-A1 | Powder composition, a dispersion of powder in oil, and a cosmetic comprising the same | SPECC1L, FANCD2, ALG1 | GLA 766/4885TDP1 3758/4885AKR1B10 729/4885 |
| US-20090203802-A1 | POWDER COMPOSITION, A DISPERSION OF POWDER IN OIL, AND A COSMETIC COMPRISING THE SAME | FANCD2, SPECC1L, ALG1 | GLA 821/4885TDP1 3358/4885AKR1B10 761/4885 |
| US-20240315950-A1 | ORGANOPOLYSILOXANE AND COSMETIC CONTAINING SAME | ALG1, ALG8, PIGS | GLA 34/4885TDP1 2009/4885AKR1B10 2045/4885 |
| US-20070207176-A1 | Powder treated with a power treating agent comprising an organopolysiloxane and cosmetic comprising the powder | RAD54L, H1-3, H1-0 | GLA 866/4885TDP1 2450/4885AKR1B10 2261/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.