Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | NQO2 | P16083 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 7/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HTR1D | P28221 | 1/20 | 0.42 |
| ▸ | HTR1B | P28222 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 4/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4448335 | 0.89 | RAB9A (0.44) | RAB9ANPC1NQO2CASP3SENP7 | |
| SCHEMBL2816719 | 0.89 | NPC1 (0.53) | RAB9ANPC1NQO2CASP3SENP7 | |
| SCHEMBL2816881 | 0.88 | RAB9A (0.54) | RAB9ANPC1NQO2CASP3SENP7 | |
| SCHEMBL2816286 | 0.86 | RAB9A (0.54) | RAB9ANPC1NQO2CASP3SENP7 | |
| SCHEMBL2815613 | 0.80 | NPC1 (0.57) | RAB9ANPC1NQO2CASP3SENP7 | |
| SCHEMBL4437668 | 0.80 | NPC1 (0.45) | RAB9ANPC1NQO2CASP3SENP7 | |
| SCHEMBL2814757 | 0.78 | NPC1 (0.52) | RAB9ANPC1NQO2CASP3SENP7 | |
| SCHEMBL2817574 | 0.78 | NPC1 (0.54) | RAB9ANPC1NQO2CASP3SENP7 | |
| SCHEMBL2816495 | 0.77 | NPC1 (0.53) | RAB9ANPC1NQO2CASP3SENP7 | |
| SCHEMBL2819873 | 0.77 | NPC1 (0.53) | RAB9ANPC1NQO2CASP3SENP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2134676-A2 | NOVEL BENZAMIDE DERIVATIVES AS MODULATORS OF THE FOLLICLE STIMULATING HORMONE | Addex Pharma SA (CH) | 2009-12-23 | — | — | EP | disclosed |
| WO-2008117175-A2 | NOVEL BENZAMIDE DERIVATIVES AS MODULATORS OF THE FOLLICLE STIMULATING HORMONE | ADDEX PHARMA SA (CH) | 2008-10-02 | — | — | WO | disclosed |