⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23897421 | 0.93 | TAAR1 (0.72) | — | |
| SCHEMBL16151249 | 0.87 | TAAR1 (0.58) | — | |
| SCHEMBL265338 | 0.86 | — | — | |
| SCHEMBL9855401 | 0.85 | TAAR1 (0.65) | — | |
| Hydrochloric Acid SCHEMBL289498 | 0.84 | — | — | |
| SCHEMBL10521145 | 0.83 | TAAR1 (0.62) | — | |
| SCHEMBL19824769 | 0.82 | — | — | |
| SCHEMBL8671494 | 0.80 | TAAR1 (0.71) | — | |
| SCHEMBL5877900 | 0.78 | CYP17A1 (0.50) | — | |
| SCHEMBL2009601 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118647270-A | Novel derivatives of non-coding amino acids and their use as herbicides | 福提费斯特有限公司 | 2024-09-13 | — | — | CN | claimed |
| WO-2023131951-A1 | NOVEL DERIVATIVES OF NON-CODED AMINO ACIDS AND THEIR USE AS HERBICIDES | FORTEPHEST LTD. (IL) | 2023-07-13 | — | — | WO | claimed |
| EP-3658550-A1 | NEW PROPANAMINE DERIVATIVES FOR TREATING PAIN AND PAIN RELATED CONDITIONS | ESTEVE PHARMACEUTICALS, S.A. (ES) | 2020-06-03 | — | — | EP | claimed |
| WO-2019020792-A1 | NEW PROPANAMINE DERIVATIVES FOR TREATING PAIN AND PAIN RELATED CONDITIONS | ESTEVE PHARMACEUTICALS, S.A. (ES) | 2019-01-31 | — | — | WO | claimed |
| CN-103588961-B | A kind of preparation method of the polythiofuran derivative conducting polymer composite of uV curable | 江南大学 | 2016-06-22 | — | — | CN | claimed |
| CN-118647270-A | Novel derivatives of non-coding amino acids and their use as herbicides | 福提费斯特有限公司 | 2024-09-13 | — | — | CN | disclosed |
| US-20240284907-A1 | NOVEL DERIVATIVES OF NON-CODED AMINO ACIDS AND THEIR USE AS HERBICIDES | FORTEPHEST LTD. (IL) | 2024-08-29 | — | — | US | disclosed |
| WO-2023131951-A1 | NOVEL DERIVATIVES OF NON-CODED AMINO ACIDS AND THEIR USE AS HERBICIDES | FORTEPHEST LTD. (IL) | 2023-07-13 | — | — | WO | disclosed |
| EP-3838900-A1 | 3-ARYLOXY-3-ARYL-PROPYLAMINE COMPOUND AND USES THEREOF | Zhangzhou Pien Tze Huang Pharmaceutical Co., Ltd (CN) | 2021-06-23 | — | — | EP | disclosed |
| EP-3658550-A1 | NEW PROPANAMINE DERIVATIVES FOR TREATING PAIN AND PAIN RELATED CONDITIONS | ESTEVE PHARMACEUTICALS, S.A. (ES) | 2020-06-03 | — | — | EP | disclosed |
| EP-3317271-B1 | INHIBITORS OF EZH2 (ENHANCER OF ZESTE HOMOLOG 2) | GLAXOSMITHKLINE IP NO 2 LTD (GB) | 2020-05-13 | — | — | EP | disclosed |
| WO-2019020792-A1 | NEW PROPANAMINE DERIVATIVES FOR TREATING PAIN AND PAIN RELATED CONDITIONS | ESTEVE PHARMACEUTICALS, S.A. (ES) | 2019-01-31 | — | — | WO | disclosed |
| CN-1019113-B | Process for preparing 3-arylhydrido-3-substituted propanamines | LILLY CO ELI (US) | 1992-11-18 | — | — | CN | disclosed |
| US-4933325-A | ANALGESICS, HYPOTENSIVE AGENTS | G. D. SEARLE & CO. (US) | 1990-06-12 | — | — | US | disclosed |
| US-4880829-A | ANALGESICS, HYPOTENSIVE AGENTS | G. D. SEARLE AND COMPANY (US) | 1989-11-14 | — | — | US | disclosed |
| US-4847241-A | ANALGESICS | G. D. SEARLE & CO. (US) | 1989-07-11 | — | — | US | disclosed |
| US-4822775-A | ANALGESICS | G. D. SEARLE & CO. (US) | 1989-04-18 | — | — | US | disclosed |
| US-4758675-A | 3-thiophene-substituted tyrosyl dipeptide amides | G. D. SEARLE & CO. (US) | 1988-07-19 | — | — | US | disclosed |
| CN-87108175-A | The propylamine that 3-aryloxy-3-replaces | — | 1988-07-06 | — | — | CN | disclosed |
| EP-0215297-A2 | Substituted dipeptide amides | G.D. Searle & Co. (US) | 1987-03-25 | — | — | EP | disclosed |