Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.65 |
| ▸ | DRD2 | P14416 | 2/20 | 0.52 |
| ▸ | DRD3 | P35462 | 2/20 | 0.52 |
| ▸ | NAAA | Q02083 | 1/20 | 0.45 |
| ▸ | GLS | O94925 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KDM4A | O75164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.35 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10521145 | 0.97 | TAAR1 (0.62) | TAAR1DRD2DRD3NAAAGLS | |
| SCHEMBL827374 | 0.89 | TAAR1 (0.54) | TAAR1DRD2DRD3NAAAGLS | |
| SCHEMBL868922 | 0.89 | TAAR1 (0.54) | TAAR1DRD2DRD3NAAAGLS | |
| SCHEMBL1309811 | 0.89 | TAAR1 (0.54) | TAAR1DRD2DRD3NAAAGLS | |
| SCHEMBL869295 | 0.89 | DRD2 (0.58) | TAAR1DRD2DRD3ALDH1A1HSD17B10 | |
| SCHEMBL23897421 | 0.89 | TAAR1 (0.72) | TAAR1DRD2DRD3NAAAGRM2 | |
| SCHEMBL6513404 | 0.89 | TAAR1 (0.54) | TAAR1DRD2DRD3NAAAGLS | |
| SCHEMBL8671494 | 0.88 | TAAR1 (0.71) | TAAR1DRD2DRD3NAAANPC1 | |
| SCHEMBL151264 | 0.87 | DRD2 (0.56) | TAAR1DRD2DRD3ALDH1A1HSD17B10 | |
| SCHEMBL2091328 | 0.87 | TAAR1 (0.52) | TAAR1DRD2DRD3NAAAGLS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3007278-A | — | — | None | — | — | JP | disclosed |
| JP-H037278-A | THIOPHENE COMPOUND AND PRODUCTION THEREOF | AGENCY OF IND SCIENCE & TECHNOL | 1991-01-14 | — | — | JP | disclosed |