⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2682411 | 1.00 | — | — | |
| SCHEMBL2681250 | 1.00 | — | — | |
| SCHEMBL10899246 | 0.77 | — | — | |
| SCHEMBL23391630 | 0.74 | — | — | |
| SCHEMBL695929 | 0.74 | — | — | |
| SCHEMBL28217985 | 0.74 | — | — | |
| SCHEMBL27481858 | 0.74 | — | — | |
| SCHEMBL9807933 | 0.72 | — | — | |
| SCHEMBL6309164 | 0.72 | — | — | |
| SCHEMBL28632852 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7592480-B2 | Process for producing optically active carboxylic acid | AJINOMOTO CO., INC. (JP) | 2009-09-22 | — | — | US | claimed |
| EP-0524604-B1 | Process for the preparations of S-(+)-2,2-dimethyl-cyclopropane carboxamid by genetically engineered microorganismes | LONZA AG (CH) | 1998-10-14 | — | — | EP | claimed |
| EP-0502525-B1 | Biotechnological process for the production of S-(+)-2,2-dimethylcyclopropanecarboxamide and R-(-)-2,2-dimethylcyclopropanecarboxylic acid | LONZA AG (CH) | 1996-06-26 | — | — | EP | claimed |
| CN-114196659-B | Amidase mutant, coding gene, engineering bacteria and application thereof | 浙江工业大学 | 2024-02-13 | — | — | CN | disclosed |
| CN-114196659-A | Amidase mutant, coding gene, engineering bacterium and application thereof | 浙江工业大学 | 2022-03-18 | — | — | CN | disclosed |