⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23391630 | 1.00 | — | — | |
| SCHEMBL28217985 | 1.00 | — | — | |
| SCHEMBL9019375 | 0.78 | — | — | |
| SCHEMBL3714633 | 0.76 | — | — | |
| SCHEMBL1767015 | 0.76 | — | — | |
| SCHEMBL4448362 | 0.74 | — | — | |
| SCHEMBL2681250 | 0.74 | — | — | |
| SCHEMBL6309164 | 0.74 | — | — | |
| SCHEMBL2682411 | 0.74 | — | — | |
| SCHEMBL6599692 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12247037-B2 | 1-(2,6-diazaspiro[3.3]heptan-6-yl)-5,6-dihydro-4h-benzo[f][1,2,4]triazolo[4,3-A][1,4]diazepine derivatives and related compounds as vasopressin antagonists for the treatment of neuro-psychological disorders | Neumora Therapeutics, Inc. (US) | 2025-03-11 | — | — | US | disclosed |
| EP-3894414-B1 | 1-(2,6-DIAZASPIRO[3.3]HEPTAN-6-YL)-5,6-DIHYDRO-4H-BENZO[F][1,2,4]TRIAZOLO[4,3-A][1,4]DIAZEPINE DERIVATIVES AS VASOPRESSIN ANTAGONISTS FOR THE TREATMENT OF NEURO-PSYCHOLOGICAL DISORDERS | NEUMORA THERAPEUTICS INC (US) | 2024-04-10 | — | — | EP | disclosed |
| CN-116514897-B | Cyclopropane or cyclopropene compound and application thereof | 暨南大学 | 2024-03-29 | — | — | CN | disclosed |
| US-11905240-B2 | Cyclopropyl ethylene compound and arthropod pest control composition containing same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2024-02-20 | — | — | US | disclosed |
| US-11858943-B2 | Vasopressin receptor antagonists and products and methods related thereto | Neumora Therapeutics, Inc. (US) | 2024-01-02 | — | — | US | disclosed |
| CN-116514897-A | Cyclopropane or cyclopropene compound and application thereof | 暨南大学 | 2023-08-01 | — | — | CN | disclosed |
| US-11649244-B2 | Method for synthesizing diaza-bridged compound and a diaza-bridged compound | LinkChem Co., Ltd., Shanghai (CN) | 2023-05-16 | — | — | US | disclosed |
| US-20230093235-A1 | VASOPRESSIN RECEPTOR ANTAGONISTS AND PRODUCTS AND METHODS RELATED THERETO | Neumora Therapeutics, Inc. | 2023-03-23 | — | — | US | disclosed |
| US-20230084719-A1 | 1-(2,6-DIAZASPIRO[3.3]HEPTAN-6-YL)-5,6-DIHYDRO-4H-BENZO[F][1,2,4]TRIAZOLO[4,3-A][1,4]DIAZEPINE DERIVATIVES AND RELATED COMPOUNDS AS VASOPRESSIN ANTAGONISTS FOR THE TREATMENT OF NEURO-PSYCHOLOGICAL DISORDERS | BLACKTHORN THERAPEUTICS, INC. | 2023-03-16 | — | — | US | disclosed |
| EP-3634963-B1 | 1-(2-AZASPIRO[3.3]HEPTAN-6-YL)-5,6-DIHYDRO-4H-BENZO[F][1,2,4]TRIAZOLO[4,3-A][1,4]DIAZEPINE DERIVATIVES AS V1A RECEPTOR ANTAGONISTS FOR TREATING NEUROPSYCHOLOGICAL DISORDERS | BLACKTHORN THERAPEUTICS INC (US) | 2023-02-22 | — | — | EP | disclosed |
| WO-2010121918-A1 | PROLINE DERIVATIVES AS CATHEPSIN INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2010-10-28 | — | — | WO | disclosed |
| US-20100267722-A1 | NOVEL PROLINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2010-10-21 | — | — | US | disclosed |
| EP-2238128-A2 | HETEROCYCLIC PYRAZOLE-CARBOXAMIDES AS P2Y12 ANTAGONISTS | Sanofi-Aventis (FR) | 2010-10-13 | — | — | EP | disclosed |
| EP-2111756-A1 | Pest control agents | MEIJI SEIKA KAISHA LTD. (JP) | 2009-10-28 | — | — | EP | disclosed |
| WO-2009080226-A2 | HETEROCYCLIC PYRAZOLE-CARBOXAMIDES AS P2Y12 ANTAGONISTS | SANOFIS-AVENTIS (FR) | 2009-07-02 | — | — | WO | disclosed |
| US-20090137634-A1 | Pest control agents | MITSUI CHEMICALS CROP & LIFE SOLUTIONS, INC. (JP) | 2009-05-28 | — | — | US | disclosed |
| EP-1889540-A1 | PEST CONTROL AGENT | MEIJI SEIKA KAISHA LTD. (JP) | 2008-02-20 | — | — | EP | disclosed |
| EP-0436348-B1 | Pyridyl cyclopropane derivatives with fungicidal activity | ZENECA LTD (GB) | 1996-11-13 | — | — | EP | disclosed |
| US-5126338-A | FUNGICIDES WHICH ARE N-PYRIDYL-CYCLOPROPANE CARBOXAMIDES OR DERIVATIVES THEREOF | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-06-30 | — | — | US | disclosed |
| EP-0436348-A2 | Pyridyl cyclopropane derivatives with fungicidal activity | ZENECA LIMITED (GB) | 1991-07-10 | — | — | EP | disclosed |