SCHEMBL4448627

SCHEMBL4448627

[CH2]CC(=O)NC1CC(C)(C)N(C)C(C)(C)C1

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAOB P27338 2/20 0.36
HDAC4 P56524 1/20 0.36
HDAC6 Q9UBN7 1/20 0.36
GAA P10253 3/20 0.36
FLT3 P36888 1/20 0.35
TYRO3 Q06418 1/20 0.35
MERTK Q12866 1/20 0.35
GAS6 Q14393 1/20 0.35
KDM4E B2RXH2 3/20 0.34
HTT P42858 1/20 0.33
KMT2A Q03164 3/20 0.33
SIGMAR1 Q99720 1/20 0.33
EPHX1 P07099 1/20 0.31
MEN1 O00255 1/20 0.31
POLB P06746 1/20 0.31
MAPT P10636 1/20 0.31
RECQL P46063 1/20 0.31
USP2 O75604 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11046524 0.87 MAOB (0.39) MAOBHDAC4HDAC6GAAFLT3
SCHEMBL8771887 0.84 MAOB (0.37) MAOBHDAC4HDAC6GAAFLT3
SCHEMBL26082900 0.82 MAOB (0.36) MAOBHDAC4HDAC6GAAFLT3
SCHEMBL228314 0.82 HDAC4 (0.38) MAOBHDAC4HDAC6GAAFLT3
SCHEMBL13298035 0.81 SMN1; SMN2 (0.47) HDAC6GAAFLT3TYRO3MERTK
SCHEMBL9456416 0.79 EPHX2 (0.40) HDAC4HDAC6GAAKDM4EKMT2A
SCHEMBL10156196 0.78 GAA (0.39) MAOBHDAC4HDAC6GAAFLT3
SCHEMBL9300620 0.78 HTT (0.41) MAOBHDAC4HDAC6GAAFLT3
SCHEMBL28889135 0.77 HDAC4 (0.39) MAOBHDAC4HDAC6GAAFLT3
SCHEMBL8613134 0.77 HDAC4 (0.39) HDAC4HDAC6GAAFLT3TYRO3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8609789-B2 Oligomeric and polymeric aromatic phosphonic acids, their blends, processes for preparing them and uses as polyelectrolytes BASF SE (DE) 2013-12-17 US disclosed
US-20120298007-A1 PROCESS FOR PRODUCING CELLULOSE ESTER FILM, CELLULOSE ESTER FILM, POLARIZATION PLATE AND DISPLAY UNIT KONICA MINOLTA OPTO, INC. (JP) 2012-11-29 US disclosed
US-20090306361-A1 PROCESS FOR PRODUCING CELLULOSE ESTER FILM, CELLULOSE ESTER FILM, POLARIZATION PLATE AND DISPLAY UNIT KONICA MINOLTA OPTO, INC. (JP) 2009-12-10 US disclosed
US-20090017360-A1 OLIGOMERIC AND POLYMERIC AROMATIC PHOSPHONIC ACIDS, THEIR BLENDS, PROCESSES FOR PREPARING THEM AND USES AS POLYELECTROLYTES BASF SE (DE) 2009-01-15 US disclosed
US-20060233973-A1 Cellulose ester film, manufacturing method thereof, optical film, polarizing plate and liquid crystal display KONICA MINOLTA OPTO, INC. 2006-10-19 US disclosed
US-5025048-A Oxygen resistant, storage-stable curable polysiloxanes hydrosilated by a polycyclic polyene and a compound containing an amine and a hydroxy, both sterically hindered HERCULES INCORPORATED (US) 1991-06-18 US disclosed
US-4198334-A HEAT, LIGHT, OXIDATION RESISTANCE, PLASTICS CIBA-GEIGY CORPORATION (US) 1980-04-15 US disclosed