SCHEMBL4448701

SCHEMBL4448701

CCCCCCCCC=CCCCCCCCCOCCCCCCCCCCC

nearest known ligand 0.79

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
LPAR1 Q92633 1/20 0.57
LPAR2 Q9HBW0 1/20 0.57
LPAR3 Q9UBY5 1/20 0.57
FAAH O00519 2/20 0.56
TRPV1 Q8NER1 1/20 0.56
MEN1 O00255 1/20 0.54
THRB P10828 1/20 0.54
HTT P42858 1/20 0.54
KMT2A Q03164 1/20 0.54
MAPT P10636 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL755636 1.00 LPAR1 (0.57) LPAR1LPAR2LPAR3FAAHTRPV1
SCHEMBL9751433 1.00 LPAR1 (0.57) LPAR1LPAR2LPAR3FAAHTRPV1
SCHEMBL44028 1.00 LPAR1 (0.57) LPAR1LPAR2LPAR3FAAHTRPV1
SCHEMBL2901529 1.00 LPAR1 (0.57) LPAR1LPAR2LPAR3FAAHTRPV1
SCHEMBL5364867 1.00 LPAR1 (0.57) LPAR1LPAR2LPAR3FAAHTRPV1
SCHEMBL1070643 1.00 LPAR1 (0.57) LPAR1LPAR2LPAR3FAAHTRPV1
SCHEMBL24398977 1.00 LPAR1 (0.57) LPAR1LPAR2LPAR3FAAHTRPV1
SCHEMBL11576564 1.00 LPAR1 (0.57) LPAR1LPAR2LPAR3FAAHTRPV1
SCHEMBL21924992 1.00 LPAR1 (0.57) LPAR1LPAR2LPAR3FAAHTRPV1
SCHEMBL20774497 1.00 LPAR1 (0.57) LPAR1LPAR2LPAR3FAAHTRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090203802-A1 POWDER COMPOSITION, A DISPERSION OF POWDER IN OIL, AND A COSMETIC COMPRISING THE SAME KAMEI MASANAO 2009-08-13 US disclosed
EP-1416016-B1 Powder composition, a dispersion of powder in oil, and a cosmetic preparation comprising polyglycerine modified silicone SHINETSU CHEMICAL CO (JP) 2008-08-13 EP disclosed
US-20060165629-A1 Powder composition, a dispersion of powder in oil, and a cosmetic comprising the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2006-07-27 US disclosed
US-20040091439-A1 Powder composition, a dispersion of powder in oil, and a cosmetic comprising the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2004-05-13 US disclosed
EP-1416016-A1 Powder composition, a dispersion of powder in oil, and a cosmetic preparation comprising polyglycerine modified silicone Shin-Etsu Chemical Co., Ltd. (JP) 2004-05-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060165629-A1 Powder composition, a dispersion of powder in oil, and a cosmetic comprising the same SPECC1L, FANCD2, ALG1 LPAR1 756/4885LPAR2 1141/4885LPAR3 643/4885
US-20040091439-A1 Powder composition, a dispersion of powder in oil, and a cosmetic comprising the same SPECC1L, SIK2, PLIN3 LPAR1 1735/4885LPAR2 2296/4885LPAR3 1595/4885
US-20090203802-A1 POWDER COMPOSITION, A DISPERSION OF POWDER IN OIL, AND A COSMETIC COMPRISING THE SAME FANCD2, SPECC1L, ALG1 LPAR1 710/4885LPAR2 1003/4885LPAR3 612/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.