Alcohol — predicted protein targets

Known targets — ChEMBL curated mechanism

MMP1 MMP13 MMP7 MMP8 pol rplA rplB rplC rplD rplE rplF rplJ rplK rplL rplM rplN rplO rplP rplQ rplR rplS rplT rplU rplV rplW rplX rplY rpmA rpmB rpmC rpmD rpmE rpmF rpmG rpmH rpmI rpmJ rpsA rpsB rpsC rpsD rpsE rpsF rpsG rpsH rpsI rpsJ rpsK rpsL rpsM rpsN rpsO rpsP rpsQ rpsR rpsS rpsT rpsU ykgM ykgO

The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 3)

	gene	UniProt	supporting neighbours	confidence
▸	TSHR	P16473	4/20	0.43

▸	ALDH1A1	P00352	2/20	0.43

▸	TDP1	Q9NUW8	2/20	0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL208586	0.91	—	—
Ether SCHEMBL9062191	0.82	TSHR (0.43)	TSHRALDH1A1TDP1
SCHEMBL21587465	0.80	TSHR (0.41)	TSHRALDH1A1TDP1
SCHEMBL5961050	0.79	—	—
SCHEMBL4450431	0.79	—	—
SCHEMBL20976965	0.76	ALDH1A1 (0.38)	TSHRALDH1A1TDP1
Alcohol SCHEMBL28270590	0.75	ALDH1A1 (0.40)	TSHRALDH1A1
Alcohol SCHEMBL9788471	0.75	ALDH1A1 (0.40)	TSHRALDH1A1
Alcohol SCHEMBL3258906	0.75	TSHR (0.47)	TSHRALDH1A1TDP1
SCHEMBL758162	0.74	—	—

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-1663916-B1	METHOD FOR CATALYTIC DEOXYGENATION OF PROCESS FLUIDS OF OLEFIN DIMERIZATION PROCESSES	NESTE OIL OYJ (FI)	2009-07-01	—	—	EP	disclosed