SCHEMBL4448880

SCHEMBL4448880

C/C(=C\CCCC1CCCCC1)C(=O)O

nearest known ligand 0.42

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.42
KDM5A P29375 3/20 0.38
PHF8 Q9UPP1 3/20 0.38
KDM2A Q9Y2K7 3/20 0.38
CD81 P60033 2/20 0.38
KDM4C Q9H3R0 2/20 0.38
KDM4A O75164 1/20 0.38
SIGMAR1 Q99720 3/20 0.37
EPHX1 P07099 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4448886 1.00 CYP1A2 (0.42) CYP1A2KDM5APHF8KDM2ACD81
SCHEMBL10816841 0.95 CYP1A2 (0.41) CYP1A2KDM5APHF8KDM2ACD81
SCHEMBL14245338 0.93 KDM5A (0.42) CYP1A2KDM5APHF8KDM2ACD81
SCHEMBL5006598 0.89 CD81 (0.40) CYP1A2KDM5APHF8KDM2ACD81
SCHEMBL3447089 0.84 CD81 (0.41) CD81
SCHEMBL8054427 0.81 SMN1; SMN2 (0.36) CD81EPHX1SMN1; SMN2
SCHEMBL25234936 0.78 LMNA (0.38) CD81EPHX1
SCHEMBL464872 0.78 LMNA (0.38) CD81EPHX1
SCHEMBL16267791 0.78 LMNA (0.38) CD81EPHX1
SCHEMBL1770285 0.78 LMNA (0.38) CD81EPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1680276-B1 MULTILAYERED FILM MADE OF (METH)ACRYLATE COPOLYMER AND POLYCARBONATE EVONIK ROEHM GMBH (DE) 2009-11-18 EP disclosed
EP-1680276-A1 MULTILAYERED FILM MADE OF (METH)ACRYLATE COPOLYMER AND POLYCARBONATE Röhm GmbH & Co. KG (DE) 2006-07-19 EP disclosed
WO-2005051657-A1 MULTILAYERED FILM MADE OF (METH)ACRYLATE COPOLYMER AND POLYCARBONATE Röhm GmbH & Co. KG (DE) 2005-06-09 WO disclosed
EP-0372213-B1 PROTECTIVE METHYCRYLATE LAYER FOR POLYCARBONATE, CONTAINING A UV ABSORBER RÖHM GMBH (DE) 1993-05-19 EP disclosed
EP-0297285-B1 COMPATIBLE BLENDS OF POLYCARBONATE AND POLYMETHACRYLATE RÖHM GMBH (DE) 1992-10-14 EP disclosed
EP-0368094-B1 IMPACT-RESISTANT PROTECTION METHACRYLATE LAYER CONTAINING A UV ABSORBER FOR POLYCARBONATE RÖHM GMBH (DE) 1992-05-06 EP disclosed
EP-0372213-A1 Protective methycrylate layer for polycarbonate, containing a UV absorber RÖHM GMBH (DE) 1990-06-13 EP disclosed
EP-0171755-B1 VINYL-CARBOXYLIC-ACID ESTERS RÖHM GMBH (DE) 1988-05-25 EP disclosed
EP-0171755-A1 Vinyl-carboxylic-acid esters RÖHM GMBH (DE) 1986-02-19 EP disclosed