SCHEMBL444907

SCHEMBL444907

OP(OCc1ccccc1)Oc1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.43
CYP1A2 P05177 2/20 0.42
CYP2C19 P33261 2/20 0.42
LMNA P02545 1/20 0.42
PTGS1 P23219 1/20 0.42
SLC6A2 P23975 1/20 0.42
PTGS2 P35354 1/20 0.42
SLC6A3 Q01959 1/20 0.42
HIF1A Q16665 1/20 0.42
HDAC6 Q9UBN7 1/20 0.42
IDO1 P14902 1/20 0.40
CYP4F2 P78329 1/20 0.40
CYP4A11 Q02928 1/20 0.40
AGXT P21549 1/20 0.39
NR4A2 P43354 2/20 0.39
ALDH1A1 P00352 4/20 0.38
MAOB P27338 3/20 0.38
NR4A1 P22736 1/20 0.38
NR4A3 Q92570 1/20 0.38
KMT2A Q03164 3/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL51153 0.85 TSHR (0.52) TSHRCYP1A2CYP2C19LMNAPTGS1
SCHEMBL28006880 0.83 TSHR (0.50) TSHRCYP1A2CYP2C19LMNAPTGS1
Hydrochloric Acid SCHEMBL27474797 0.83 TSHR (0.50) TSHRCYP1A2CYP2C19LMNAPTGS1
SCHEMBL15021274 0.83 TSHR (0.50) TSHRCYP1A2CYP2C19LMNAPTGS1
SCHEMBL9941450 0.81 IDO1 (0.41) LMNAIDO1GAARAB9ACA1
SCHEMBL5929542 0.79 TSHR (0.46) TSHRCYP1A2CYP2C19LMNAPTGS1
SCHEMBL27626925 0.79 TSHR (0.46) TSHRCYP1A2CYP2C19LMNAPTGS1
SCHEMBL11743736 0.79 TSHR (0.46) TSHRCYP1A2CYP2C19LMNAPTGS1
SCHEMBL11651441 0.78 CYP1A2 (0.66) CYP1A2CYP2C19LMNAPTGS1SLC6A2
SCHEMBL132913 0.78 LTA4H (0.45) TSHRCYP2C19LMNAIDO1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 185 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3500614-B1 POLYESTER COMPOSITIONS WHICH COMPRISE TETRAMETHYLCYCLOBUTANEDIOL AND ETHYLENE GLYCOL FOR CALENDERING EASTMAN CHEM CO (US) 2025-08-06 EP disclosed
US-11760952-B2 Lubricant thickener systems from modified tall oil fatty acids, lubricating compositions, and associated methods INGEVITY SOUTH CAROLINA, LLC (US) 2023-09-19 US disclosed
US-20230097718-A1 BIOBASED EXTREME PRESSURE ADDITIVE FOR LUBRICATING COMPOSITIONS AND ASSOCIATED METHODS INGEVITY SOUTH CAROLINA, LLC 2023-03-30 US disclosed
US-11447601-B2 Polyester compositions which comprise tetramethylcyclobutanediol and ethylene glycol for calendering EASTMAN CHEMICAL COMPANY (US) 2022-09-20 US disclosed
US-20220220408-A1 LUBRICANT THICKENER SYSTEMS FROM MODIFIED TALL OIL FATTY ACIDS, LUBRICATING COMPOSITIONS, AND ASSOCIATED METHODS MAINSTREAM PINE PRODUCTS, LLC 2022-07-14 US disclosed
EP-3562924-B1 LOW VISCOSITY LUBRICATING OIL COMPOSITIONS FOR TURBOMACHINES EXXONMOBIL RES & ENG CO (US) 2022-05-25 EP disclosed
CN-108350004-B Preparation method of phosphorus-containing cyanohydrin ester 拜耳作物科学股份公司 2021-03-12 CN disclosed
US-10829708-B2 Composition and method for preventing or reducing engine knock and pre-ignition in high compression spark ignition engines EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2020-11-10 US disclosed
US-10774286-B2 Grease compositions with improved performance and methods of preparing and using the same EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2020-09-15 US disclosed
EP-3684895-A1 HYDRAULIC OIL COMPOSITIONS WITH IMPROVED HYDROLYTIC AND THERMO-OXIDATIVE STABILITY ExxonMobil Research and Engineering Company (US) 2020-07-29 EP disclosed
EP-1148114-A2 Lubricating oil compositions having excellent thermal stabilty, extreme pressure resistance and anti-wear performance Chevron Oronite Japan Limited (JP) 2001-10-24 EP disclosed
US-6133403-A RESOLE MIXTURE INCLUDING A SUBSTITUTED BENZYL ALCOHOL OR ETHER, ACID CURING CATALYST; IMPACT STRENGTH, FLEXIBILITY BORDEN CHEMICAL, INC. (US) 2000-10-17 US disclosed
EP-0869980-A4 REACTIVE DILUENTS FOR ACID CURABLE PHENOLIC COMPOSITIONS BORDEN INC (US) 1999-03-24 EP disclosed
CN-1209144-A Reactive diluents for acid-cured phenolic resin compositions BORDEN INC (US) 1999-02-24 CN disclosed
EP-0869980-A1 REACTIVE DILUENTS FOR ACID CURABLE PHENOLIC COMPOSITIONS Borden Chemical, Inc. (US) 1998-10-14 EP disclosed
WO-1997024385-A1 REACTIVE DILUENTS FOR ACID CURABLE PHENOLIC COMPOSITIONS BORDEN CHEMICAL, INC. (US) 1997-07-10 WO disclosed
EP-0007326-B1 AMIDINES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM. SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) 1982-01-27 EP disclosed
US-4282213-A ANTIHISTAMINES SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) 1981-08-04 US disclosed
US-4190664-A HISTAMINE ANTAGONISTS SMITHKLINE & FRENCH LABORATORIES LIMITED (GB) 1980-02-26 US disclosed
EP-0007326-A1 Amidines, their preparation and pharmaceutical compositions containing them. SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) 1980-02-06 EP disclosed