Styrene

Styrene

SCHEMBL4449073

C=CC#N.C=CC(=O)OCC.C=Cc1ccccc1

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.45
MEN1 O00255 3/20 0.45
ALDH1A1 P00352 4/20 0.44
POLB P06746 1/20 0.44
THRB P10828 1/20 0.43
SMN1; SMN2 Q16637 3/20 0.41
TSHR P16473 1/20 0.40
MAPT P10636 6/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
KDM4E B2RXH2 1/20 0.39
ADORA3 P0DMS8 1/20 0.39
HPGD P15428 1/20 0.39
XBP1 P17861 1/20 0.39
CTDSP1 Q9GZU7 1/20 0.39
MCL1 Q07820 1/20 0.39
PDCD1 Q15116 1/20 0.38
CD274 Q9NZQ7 1/20 0.38
LMNA P02545 2/20 0.38
DHFR P00374 1/20 0.38
ALOX12 P18054 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL27854665 0.97 KMT2A (0.43) KMT2AMEN1ALDH1A1POLBTHRB
Styrene SCHEMBL138624 0.91 MEN1 (0.53) KMT2AMEN1ALDH1A1THRBSMN1; SMN2
Styrene SCHEMBL27683722 0.91 MEN1 (0.53) KMT2AMEN1ALDH1A1THRBSMN1; SMN2
Styrene SCHEMBL1087426 0.88 MEN1 (0.50) KMT2AMEN1ALDH1A1THRBSMN1; SMN2
Styrene SCHEMBL8175732 0.88 MEN1 (0.50) KMT2AMEN1ALDH1A1THRBSMN1; SMN2
Styrene SCHEMBL11061984 0.88 MEN1 (0.50) KMT2AMEN1ALDH1A1THRBSMN1; SMN2
Styrene SCHEMBL295504 0.87 TSHR (0.56) ALDH1A1THRBTSHRL3MBTL1KDM4E
Styrene SCHEMBL5613413 0.86 CYP3A4 (0.44) KMT2AMEN1ALDH1A1THRBSMN1; SMN2
Acrylic Acid Ethyl Ester SCHEMBL4214606 0.85 MAPT (0.41) KMT2AMEN1ALDH1A1POLBTHRB
Styrene SCHEMBL7652390 0.85 MEN1 (0.47) KMT2AMEN1ALDH1A1POLBTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102725349-B Silicon-based impact modifier consisting of a graft copolymer having a core-shell structure, and thermoplastic composition having same CHEIL IND INC 2014-11-26 CN claimed
CN-102532191-B Novel phosphorus compound, method for preparing the same, and flame retardant thermoplastic resin composition comprising the same CHEIL IND INC 2014-11-12 CN claimed
US-8410203-B2 Phosphorus compound, method of preparing the same and flame retardant thermoplastic resin composition including the same CHEIL INDUSTRIES INC. (KR) 2013-04-02 US claimed
CN-101228222-B Polymer composition comprising a polymer resin and a carboxylate phosphinate salt compound CHEIL IND INC 2012-11-07 CN claimed
CN-102725349-A Silicon-based impact modifier consisting of a graft copolymer having a core-shell structure, and thermoplastic composition having same CHEIL IND INC 2012-10-10 CN claimed
CN-102532191-A Novel phosphorus compound, method for preparing the same, and flame retardant thermoplastic resin composition comprising the same CHEIL IND INC 2012-07-04 CN claimed
US-20120165444-A1 Novel Phosphorus Compound, Method of Preparing the Same and Flame Retardant Thermoplastic Resin Composition Including the Same CHEIL INDUSTRIES INC. (KR) 2012-06-28 US claimed
EP-2468814-A1 Novel Phosphorus Compound, Method of Preparing the Same and Flame Retardant Thermoplastic Resin Composition Including the Same Cheil Industries Inc. (KR) 2012-06-27 EP claimed
CN-101228222-A Polymer composition comprising a polymer resin and a carboxylate phosphinate salt compound CHEIL IND INC (KR) 2008-07-23 CN claimed
CN-109910405-B Lightweight ultrahigh-impact composite sheet and preparation method thereof 浙江千禧龙纤特种纤维股份有限公司 2021-09-07 CN disclosed
US-9346949-B2 High reflectance polycarbonate SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2016-05-24 US disclosed
CN-102725349-B Silicon-based impact modifier consisting of a graft copolymer having a core-shell structure, and thermoplastic composition having same CHEIL IND INC 2014-11-26 CN disclosed
CN-102532191-B Novel phosphorus compound, method for preparing the same, and flame retardant thermoplastic resin composition comprising the same CHEIL IND INC 2014-11-12 CN disclosed
US-20140226342-A1 HIGH REFLECTANCE POLYCARBONATE SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2014-08-14 US disclosed
EP-0884361-A1 Low gloss thermoplastic resin composition GENERAL ELECTRIC COMPANY (US) 1998-12-16 EP disclosed
US-5594035-A Reclamation of polymers, that contain styrene in the polymeric backbone, using a water soluble solvent based reclamation process BASF CORPORATION (US) 1997-01-14 US disclosed
CN-1129719-A Impact modified vinyl chloride resin composition, and graft copolymer compositions GEN ELECTRIC (US) 1996-08-28 CN disclosed
CN-1127762-A Process thermoplastic compositions and emulsion graft copolymer utilizing a polyacid GEN ELECTRIC (US) 1996-07-31 CN disclosed
US-5530062-A FOR BLENDS OF ADDITION POLYMERS GENERAL ELECTRIC COMPANY (US) 1996-06-25 US disclosed
CN-1104224-A Process for the manufacture of low gloss resins GEN ELECTRIC (US) 1995-06-28 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120165444-A1 Novel Phosphorus Compound, Method of Preparing the Same and Flame Retardant Thermoplastic Resin Composition Including the Same RPP30, RER1, TAF11 KMT2A 1293/4885MEN1 3157/4885ALDH1A1 2208/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.