SCHEMBL4449296

SCHEMBL4449296

O=S(=O)(O)C1(F)C(F)(F)C(F)(F)C(F)(F)C1(F)F

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
CA5A P35218 1/20 0.31
CA5B Q9Y2D0 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL712910 1.00 TSHR (0.35) TSHRTDP1CA5ACA5B
SCHEMBL6152272 1.00 TSHR (0.35) TSHRTDP1CA5ACA5B
SCHEMBL11857618 0.97 TSHR (0.33) TSHRTDP1
SCHEMBL5708404 0.97 TSHR (0.33) TSHRTDP1
SCHEMBL5708410 0.97 TSHR (0.33) TSHRTDP1
SCHEMBL7651161 0.97 TSHR (0.33) TSHRTDP1
SCHEMBL11321071 0.97 TSHR (0.33) TSHRTDP1
SCHEMBL11313021 0.97 TSHR (0.33) TSHRTDP1
SCHEMBL17598899 0.84
SCHEMBL713766 0.83 MEN1 (0.42) TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090326116-A1 POLYCARBONATE COMPOSITIONS HAVING ANTISTATIC ENHANCERS, METHOD OF PREPARING, AND ARTICLES COMPRISING THE SAME SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2009-12-31 US claimed
EP-4269543-B1 POLYSILOXANE HYDRAULIC FLUIDS COMMW SCIENT IND RES ORG (AU) 2026-03-04 EP disclosed
US-12227713-B2 Polysiloxane hydraulic fluids THE BOEING COMPANY (US) 2025-02-18 US disclosed
US-20250011671-A9 POLYSILOXANE HYDRAULIC FLUIDS THE BOEING COMPANY 2025-01-09 US disclosed
EP-4269543-A2 POLYSILOXANE HYDRAULIC FLUIDS Commonwealth Scientific and Industrial Research Organisation (AU) 2023-11-01 EP disclosed
EP-3455282-B1 POLYSILOXANE HYDRAULIC FLUIDS COMMW SCIENT IND RES ORG (AU) 2023-11-01 EP disclosed
US-20230323233-A1 POLYSILOXANE HYDRAULIC FLUIDS BOEING CO (US) 2023-10-12 US disclosed
CN-109790293-B Polysiloxane hydraulic fluid 联邦科学和工业研究组织 2022-08-12 CN disclosed
US-11299688-B2 Polysiloxane hydraulic fluids THE BOEING COMPANY (US) 2022-04-12 US disclosed
US-20190284494-A1 POLYSILOXANE HYDRAULIC FLUIDS THE BOEING COMPANY 2019-09-19 US disclosed
EP-3455282-A1 POLYSILOXANE HYDRAULIC FLUIDS Commonwealth Scientific and Industrial Research Organisation (AU) 2019-03-20 EP disclosed
WO-2017193174-A1 POLYSILOXANE HYDRAULIC FLUIDS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2017-11-16 WO disclosed
US-8623948-B2 Polycarbonate compositions having antistatic enhancers, method of preparing, and articles comprising the same SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2014-01-07 US disclosed
US-20090326116-A1 POLYCARBONATE COMPOSITIONS HAVING ANTISTATIC ENHANCERS, METHOD OF PREPARING, AND ARTICLES COMPRISING THE SAME SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2009-12-31 US disclosed