SCHEMBL6152272

SCHEMBL6152272

O=S(=O)(O)C1(F)C(F)(F)C(F)(F)C1(F)F

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
CA5A P35218 1/20 0.31
CA5B Q9Y2D0 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4449296 1.00 TSHR (0.35) TSHRTDP1CA5ACA5B
SCHEMBL712910 1.00 TSHR (0.35) TSHRTDP1CA5ACA5B
SCHEMBL11857618 0.97 TSHR (0.33) TSHRTDP1
SCHEMBL5708404 0.97 TSHR (0.33) TSHRTDP1
SCHEMBL5708410 0.97 TSHR (0.33) TSHRTDP1
SCHEMBL7651161 0.97 TSHR (0.33) TSHRTDP1
SCHEMBL11321071 0.97 TSHR (0.33) TSHRTDP1
SCHEMBL11313021 0.97 TSHR (0.33) TSHRTDP1
SCHEMBL17598899 0.84
SCHEMBL713766 0.83 MEN1 (0.42) TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1497374-A1 FILLER REINFORCED POLYETHER IMIDE RESIN COMPOSITION AND MOLDED ARTICLE THEREOF GENERAL ELECTRIC COMPANY (US) 2005-01-19 EP disclosed
WO-2003087226-A1 FILLER REINFORCED POLYETHER IMIDE RESIN COMPOSITION AND MOLDED ARTICLE THEREOF GENERAL ELECTRIC COMPAMY (US) 2003-10-23 WO disclosed
US-3931100-A SULFONATE GENERAL ELECTRIC COMPANY (US) 1976-01-06 US disclosed