Urea

Urea

SCHEMBL4449300

NC(N)=O.O=CC=O.O=CC=O

nearest known ligand 0.60

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.60
LMNA P02545 5/20 0.60
TDP1 Q9NUW8 2/20 0.60
OR51E2 Q9H255 1/20 0.60
ACHE P22303 1/20 0.42
TSHR P16473 3/20 0.40
FGFR4 P22455 1/20 0.40
BLM P54132 4/20 0.39
PMP22 Q01453 3/20 0.39
ALOX15 P16050 2/20 0.39
LDHA P00338 2/20 0.36
LDHB P07195 1/20 0.36
CYP3A4 P08684 3/20 0.33
NFKB1 P19838 2/20 0.33
HPGD P15428 2/20 0.33
HSD17B10 Q99714 2/20 0.33
CYP1A2 P05177 2/20 0.33
THPO P40225 2/20 0.33
EHMT2 Q96KQ7 1/20 0.33
EHMT1 Q9H9B1 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Urea SCHEMBL29737 1.00
Urea SCHEMBL899093 0.91 ALDH1A1 (0.50) ALDH1A1LMNATDP1OR51E2ACHE
Urea SCHEMBL4354955 0.91 ALDH1A1 (0.50) ALDH1A1LMNATDP1OR51E2ACHE
Carbamic Acid SCHEMBL10937836 0.86
Urea SCHEMBL28489474 0.84 ALDH1A1 (0.43) ALDH1A1LMNATDP1OR51E2ACHE
Urea SCHEMBL10535511 0.84 ALDH1A1 (0.43) ALDH1A1LMNATDP1OR51E2ACHE
Urea SCHEMBL28087197 0.84
Urea SCHEMBL20542511 0.82 ALDH1A1 (0.44) ALDH1A1LMNATDP1OR51E2TSHR
Urea SCHEMBL228057 0.80
Urea SCHEMBL1312661 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090320708-A1 RECORDING SHEET WITH IMPROVED PRINT DENSITY INTERNATIONAL PAPER COMPANY (US) 2009-12-31 US disclosed