Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL390764 | 0.81 | GPR119 (0.72) | GPR119MAPTKMT2ARAB9AKDM4E | |
| SCHEMBL5261880 | 0.80 | GPR119 (0.57) | GPR119MAPTKMT2ALMNARAB9A | |
| SCHEMBL1673697 | 0.76 | GPR119 (0.53) | GPR119MAPTKMT2ALMNARAB9A | |
| SCHEMBL1673792 | 0.76 | GPR119 (0.55) | GPR119 | |
| SCHEMBL12733498 | 0.70 | GPR119 (0.86) | GPR119MAPTKMT2ALMNARAB9A | |
| SCHEMBL1673687 | 0.67 | GPR119 (0.81) | GPR119MAPTKMT2ARAB9ATP53 | |
| SCHEMBL27632009 | 0.67 | GPR119 (0.57) | GPR119MAPTKMT2ALMNAL3MBTL1 | |
| SCHEMBL6391402 | 0.67 | GPR119 (0.73) | GPR119MAPTKMT2ARAB9AKDM4E | |
| SCHEMBL5265609 | 0.66 | GPR119 (0.57) | GPR119 | |
| SCHEMBL390329 | 0.66 | GPR119 (0.82) | GPR119MAPTKMT2ARAB9ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1808168-B1 | Combination therapy for the treatment of diabetes and conditions related thereto and for the treatment of conditions ameliorated by increasing a blood GLP-1 level | ARENA PHARM INC (US) | 2009-06-03 | — | — | EP | disclosed |