SCHEMBL44494

SCHEMBL44494

C1=CSc2ccccc2C1

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
RYR2 Q92736 1/20 0.32
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31
HPGD P15428 1/20 0.31
ACHE P22303 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29750990 1.00 RYR2 (0.32) RYR2KDM4EALDH1A1HPGDACHE
Acetic Acid SCHEMBL9788860 0.87 HSD17B3 (0.36) RYR2KDM4EALDH1A1HPGD
SCHEMBL4506320 0.77 TSHR (0.33) RYR2TSHR
SCHEMBL4862184 0.77 RYR2 (0.31) RYR2
SCHEMBL13231440 0.72
SCHEMBL10713333 0.71 ACHE (0.50) KDM4EALDH1A1HPGDACHETSHR
SCHEMBL5139731 0.70 KDM4E (0.43) KDM4EALDH1A1HPGDACHE
SCHEMBL3894806 0.70
SCHEMBL4862192 0.70 ACHE (0.34) RYR2KDM4EALDH1A1HPGDACHE
SCHEMBL19752486 0.68 RYR2 (0.38) RYR2ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3929 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12595275-B2 Fluorine-containing compound and anti-cancer medical use thereof ASCENTAWITS PHARMACEUTICALS, LTD. (CN) 2026-04-07 US claimed
US-20260048156-A1 FAP-TARGETING PHARMACEUTICAL PRODUCT FOR THERAPY AND DIAGNOSIS OF CANCERS Atoms for Cure GmbH (DE) 2026-02-19 US claimed
EP-4658713-A1 METHOD FOR DEGRADING AND RECYCLING A POLYURETHANE AND THE DEGRADATION PRODUCT THEREOF Covestro Deutschland AG (DE) 2025-12-10 EP claimed
EP-3971194-B1 FLUORINE-CONTAINING COMPOUND AND ANTI-CANCER MEDICAL USE THEREOF ASCENTAWITS PHARMACEUTICALS LTD (CN) 2025-12-03 EP claimed
US-20250302831-A1 THERAPY FOR ALCOHOL-RELATED LIVER DISEASE THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS, OFFICE OF THE GENERAL COUNSEL (024) 2025-10-02 US claimed
WO-2025111482-A1 COMPLEXING AGENT SALT FORMULATIONS OF PHARMACEUTICAL COMPOUNDS AT LOW STOICHIOMETRIC RATIOS BEXSON BIOMEDICAL, INC. (US) 2025-05-30 WO claimed
EP-4486395-A1 PRECURSOR MARKERS AND RADIOTRACERS WITH THREE OR MORE TARGETING VECTORS FOR THERANOSTICS USED IN NUCLEAR MEDICINE Atoms for Cure GmbH (DE) 2025-01-08 EP claimed
EP-4452326-A1 FAP-TARGETING PHARMACEUTICAL PRODUCT FOR THERAPY AND DIAGNOSIS OF CANCERS Atoms for Cure GmbH (DE) 2024-10-30 EP claimed
CN-118834240-A Fluorine-containing compound and anticancer medical application 深圳艾欣达伟医药科技有限公司 2024-10-25 CN claimed
CN-118785925-A Marker precursors and radiotracers with three or more targeting vectors for use in diagnostic nuclear medicine therapies 原子治疗有限公司 2024-10-15 CN claimed
US-5178995-A Reflectance, storage stability CANON KABUSHIKI KAISHA (JP) 1993-01-12 US claimed
EP-0463784-A2 Optical recording medium, optical recording method, and optical reproducing method CANON KABUSHIKI KAISHA (JP) 1992-01-02 EP claimed
EP-0434365-A2 HIV protease inhibitors useful for the treatment of aids MERCK & CO. INC. (US) 1991-06-26 EP claimed
EP-0271550-A1 BENZOPYRAN AND BENZOTHIOPYRAN DERIVATIVES AND COMPOSITIONS CONTAINING THEM ALKALOIDA VEGYéSZETI GYáR (HU) 1988-06-22 EP claimed
EP-0264198-A2 Optical information recording medium CANON KABUSHIKI KAISHA (JP) 1988-04-20 EP claimed
WO-1988000197-A1 BENZOPYRAN AND BENZOTHIOPYRAN DERIVATIVES AND COMPOSITIONS CONTAINING THEM ALKALOIDA VEGYE^´SZETI GYA^´R (HU) 1988-01-14 WO claimed
EP-0079683-B1 HERBICIDAL SULFONAMIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1987-05-06 EP claimed
US-4548886-A ELECTROGRAPHIC FILMS; OPTICAL RECORDING MEDIA CANON KABUSHIKI KAISHA (JP) 1985-10-22 US claimed
US-4318981-A Homogeneous specific binding assay employing an intramolecularly modulated photogenic enzyme substrate label MILES LABORATORIES, INC. (US) 1982-03-09 US claimed
US-4221806-A ANTIALLERGENS CIBA-GEIGY CORPORATION (US) 1980-09-09 US claimed