Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | CASP3 | P42574 | 2/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.41 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4442008 | 0.85 | KMT2A (0.53) | KMT2AMAPTMEN1TP53GAA | |
| SCHEMBL14113711 | 0.85 | MAPT (0.57) | KMT2AMAPTMEN1TP53GAA | |
| SCHEMBL14113440 | 0.85 | KMT2A (0.56) | KMT2AMAPTMEN1TP53GAA | |
| SCHEMBL3301646 | 0.85 | KMT2A (0.56) | KMT2AMAPTMEN1TP53GAA | |
| SCHEMBL3306261 | 0.85 | MAPT (0.57) | KMT2AMAPTMEN1TP53GAA | |
| SCHEMBL3301643 | 0.85 | KMT2A (0.56) | KMT2AMAPTMEN1TP53GAA | |
| SCHEMBL3306256 | 0.85 | MAPT (0.57) | KMT2AMAPTMEN1TP53GAA | |
| SCHEMBL3299592 | 0.81 | CASP3 (0.47) | KMT2AMAPTMEN1TP53GAA | |
| SCHEMBL3302513 | 0.81 | CASP3 (0.47) | KMT2AMAPTMEN1TP53GAA | |
| SCHEMBL14113482 | 0.81 | CASP3 (0.47) | KMT2AMAPTMEN1TP53GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2120911-A1 | AMIDE AND UREA DERIVATIVES FOR THE TREATMENT OF METABOLIC DISEASES | Prosidion Limited (GB) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008099221-A1 | AMIDE AND UREA DERIVATIVES FOR THE TREATMENT OF METABOLIC DISEASES | PROSIDION LIMITED (GB) | 2008-08-21 | — | — | WO | disclosed |