SCHEMBL444960

SCHEMBL444960

CCCCCCCCCCCCCOC(=O)C=CC(=O)OCCCCCCCCCCCCC

nearest known ligand 0.85

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 4/20 0.85
ATM Q13315 1/20 0.83
MAPT P10636 1/20 0.59
RAB9A P51151 1/20 0.59
NPSR1 Q6W5P4 1/20 0.59
NAAA Q02083 1/20 0.59
TSHR P16473 4/20 0.57
HPGD P15428 1/20 0.57
APP P05067 4/20 0.55
EPHX1 P07099 1/20 0.55
HTT P42858 2/20 0.53
SMN1; SMN2 Q16637 2/20 0.53
ALDH1A1 P00352 1/20 0.52
CYP3A4 P08684 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11680742 1.00 HCAR2 (0.85) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL440694 1.00 HCAR2 (0.85) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL9318682 1.00 HCAR2 (0.85) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL357423 1.00 HCAR2 (0.85) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL356935 1.00 HCAR2 (0.85) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL18209632 1.00 HCAR2 (0.85) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL7780534 1.00 HCAR2 (0.85) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL42963 1.00 HCAR2 (0.85) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL1305378 1.00 HCAR2 (0.85) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL10895119 1.00 HCAR2 (0.85) HCAR2ATMMAPTRAB9ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 196 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100093943-A1 REACTIVE ESTERS AS PLASTICIZERS FOR ELASTOMERS HALLSTAR INNOVATIONS CORP. (US) 2010-04-15 US claimed
US-6265517-B1 MOISTURE CURABLE SEALANT BOSTIK, INC. 2001-07-24 US claimed
EP-0751177-A2 Stabilizers for high nitrile multipolymers THE STANDARD OIL COMPANY (US) 1997-01-02 EP claimed
US-5216089-A Includes modifier comprising of alpha-beta-unsaturated carboxylic acid derivatives GENERAL ELECTRIC COMPANY (US) 1993-06-01 US claimed
US-5214109-A Modified polyphenylene ether resins having improved processability and oxidative stability GENERAL ELECTRIC COMPANY (US) 1993-05-25 US claimed
EP-0266617-B1 MODIFIED POLYPHENYLENE ETHER RESINS HAVING IMPROVED FOAMABILITY AND METHODS OF MAKING THE SAME GENERAL ELECTRIC COMPANY (US) 1992-07-15 EP claimed
EP-0266617-A2 Modified polyphenylene ether resins having improved foamability and methods of making the same GENERAL ELECTRIC COMPANY (US) 1988-05-11 EP claimed
US-4729850-A NONIONIC SURFACTANTS, POLYURETHANES, PHENOLIC RESINS, POLYISOCYANURATES THE CELOTEX CORPORATION (US) 1988-03-08 US claimed
EP-0257486-A1 Modified polyphenylene ether resins having improved processability and oxidative stability GENERAL ELECTRIC COMPANY (US) 1988-03-02 EP claimed
US-4728674-A ALPHA, BETA-UNSATURATED CARBOXYLIC ACID DERIVATIVE GENERAL ELECTRIC COMPANY (US) 1988-03-01 US claimed
US-4522877-A Extraction of polyoxyalkylene surfactants for phenolic foam stabilization THE CELOTEX CORPORATION (US) 1985-06-11 US claimed
US-4520140-A Polyoxyalkylene/unsaturated diester reaction product for cellular foam stabilization THE CELOTEX CORPORATION (US) 1985-05-28 US claimed
US-4485194-A Extraction of polyoxyalkylene surfactants for phenolic foam stabilization THE CELOTEX CORPORATION (US) 1984-11-27 US claimed
EP-0124111-A2 Unsaturated polyoxyalkylene adduct/fumarate diester reaction product for cellular foam stabilization Sloss Industries Corporation (US) 1984-11-07 EP claimed
US-4481307-A GRAFT POLYMERS THE CELOTEX CORPORATION (US) 1984-11-06 US claimed
US-4418158-A POLYURETHANE, SURFACTANT THE CELOTEX CORPORATION (US) 1983-11-29 US claimed
US-4412014-A POLYOXYALKYLENE ADDUCT REACTED WITH A CYCLIC NITROGENOUS VINYL MONOMER AND UNSATURATED DIBASIC ESTER THE CELOTEX CORPORATION (US) 1983-10-25 US claimed
EP-0070419-A2 Process for preparing cellular foam stabilizer and foam material produced thereby Celotex Corporation (US) 1983-01-26 EP claimed
US-4365024-A ADDITION-CONDENSATION COPOLYMER THE CELOTEX CORPORATION (US) 1982-12-21 US claimed
EP-0032838-A1 Extraction of polyoxyalkylene surfactants for phenolic foam stabilization Celotex Corporation (US) 1981-07-29 EP claimed