SCHEMBL357423

SCHEMBL357423

CCCCCCCCCCCCCCCCCCCCCCOC(=O)C=CC(=O)OCCCCCCCCCCCCCCCCCCCCCC

nearest known ligand 0.85

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 4/20 0.85
ATM Q13315 1/20 0.83
MAPT P10636 1/20 0.59
RAB9A P51151 1/20 0.59
NPSR1 Q6W5P4 1/20 0.59
NAAA Q02083 1/20 0.59
TSHR P16473 4/20 0.57
HPGD P15428 1/20 0.57
APP P05067 4/20 0.55
EPHX1 P07099 1/20 0.55
HTT P42858 2/20 0.53
SMN1; SMN2 Q16637 2/20 0.53
ALDH1A1 P00352 1/20 0.52
CYP3A4 P08684 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11680742 1.00 HCAR2 (0.85) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL440694 1.00 HCAR2 (0.85) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL9318682 1.00 HCAR2 (0.85) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL444960 1.00 HCAR2 (0.85) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL356935 1.00 HCAR2 (0.85) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL18209632 1.00 HCAR2 (0.85) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL7780534 1.00 HCAR2 (0.85) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL42963 1.00 HCAR2 (0.85) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL1305378 1.00 HCAR2 (0.85) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL10895119 1.00 HCAR2 (0.85) HCAR2ATMMAPTRAB9ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 134 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1391498-B1 FLUIDITY IMPROVER AND FUEL OIL COMPOSITION SANYO CHEMICAL IND LTD (JP) 2016-09-07 EP claimed
US-20050169877-A1 Process for preparing a composition using pressurized fluid, composition prepared, and uses thereof L'OREAL (FR) 2005-08-04 US claimed
US-20030118618-A1 New Method for making a water-in-oil emulsion WALTER MERTON, INC. 2003-06-26 US claimed
WO-2003034983-A2 COMPOSITIONS AND A NEW METHOD FOR MAKING A WATER-IN-OIL EMULSION WALTER MERTON, CO., INC. (US) 2003-05-01 WO claimed
US-5242782-A Flexographic printing plate ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1993-09-07 US claimed
US-4634550-A OIL ADDITIVES EXXON RESEARCH AND ENGINEERING COMPANY (US) 1987-01-06 US claimed
US-20260021219-A1 METHODS AND ABSORBENT ARTICLES FOR INHIBITING FECAL PROTEASE ACTIVITY KIMBERLY CLARK CO (US) 2026-01-22 US disclosed
US-20250313029-A1 PHOTOSENSITIVE RESIN COMPOSITION, FLEXOGRAPHIC PRINTING RAW PLATE, AND MANUFACTURING METHOD OF FLEXOGRAPHIC PRINTING PLATE ASAHI KASEI KABUSHIKI KAISHA (JP) 2025-10-09 US disclosed
US-20250199427-A1 TONER CANON KABUSHIKI KAISHA (JP) 2025-06-19 US disclosed
US-12332564-B2 Photosensitive resin composition for flexographic printing NIPPON SODA CO., LTD. (JP) 2025-06-17 US disclosed
EP-4528377-A1 PHOTOSENSITIVE RESIN COMPOSITION, FLEXOGRAPHIC PRINTING ORIGINAL PLATE, AND METHOD FOR PRODUCING FLEXOGRAPHIC PRINTING PLATE Asahi Kasei Kabushiki Kaisha (JP) 2025-03-26 EP disclosed
US-12259655-B1 Manufacturing method of flexographic printing plate and printing method ASAHI KASEI KABUSHIKI KAISHA (JP) 2025-03-25 US disclosed
US-20250076769-A1 MANUFACTURING METHOD OF FLEXOGRAPHIC PRINTING PLATE AND PRINTING METHOD ASAHI KASEI KABUSHIKI KAISHA (JP) 2025-03-06 US disclosed
US-4857433-A Electrophotographic toner for high speed electrophotography MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1989-08-15 US disclosed
US-4727010-A BLEND OF COPOLYMER OF AROMATIC VINYL, ALKYL FUMARATE WITH ANOTHER VINYL POLYMER MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1988-02-23 US disclosed
US-4634550-A OIL ADDITIVES EXXON RESEARCH AND ENGINEERING COMPANY (US) 1987-01-06 US disclosed
EP-0017927-B1 PROCESS FOR PREPARING PHOTOPOLYMERIZED ELASTOMERIC PRINTING PLATES NOT DISPLAYING SURFACE STICKINESS Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1984-09-19 EP disclosed
US-4266005-A Photosensitive elastomeric composition ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1981-05-05 US disclosed
EP-0017927-A2 Process for preparing photopolymerized elastomeric printing plates not displaying surface stickiness Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1980-10-29 EP disclosed
US-4074978-A Combination of asphaltenes with flow improver polymers to improve the flow properties of high boiling fuel oils EXXON RESEARCH & ENGINEERING CO. (US) 1978-02-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260021219-A1 METHODS AND ABSORBENT ARTICLES FOR INHIBITING FECAL PROTEASE ACTIVITY CUTA, CTRL, PEPD HCAR2 4668/4885ATM 1399/4885MAPT 1996/4885
US-20050169877-A1 Process for preparing a composition using pressurized fluid, composition prepared, and uses thereof KRT18, KRTCAP2, CKAP4 HCAR2 4774/4885ATM 2357/4885MAPT 126/4885
US-20030118618-A1 New Method for making a water-in-oil emulsion DEGS1, DGAT2, DGAT1 HCAR2 592/4885ATM 4033/4885MAPT 1681/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.