Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.67 |
| ▸ | PPARD | Q03181 | 5/20 | 0.67 |
| ▸ | PPARA | Q07869 | 5/20 | 0.67 |
| ▸ | F7 | P08709 | 5/20 | 0.67 |
| ▸ | F3 | P13726 | 5/20 | 0.67 |
| ▸ | MAPT | P10636 | 4/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.67 |
| ▸ | TERT | O14746 | 3/20 | 0.67 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.67 |
| ▸ | BLM | P54132 | 3/20 | 0.67 |
| ▸ | FABP4 | P15090 | 3/20 | 0.67 |
| ▸ | LMNA | P02545 | 3/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.67 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.67 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.67 |
| ▸ | RECQL | P46063 | 2/20 | 0.67 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.67 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4449624 | 1.00 | PPARG (0.67) | PPARGPPARDPPARAF7F3 | |
| SCHEMBL5379264 | 1.00 | PPARG (0.67) | PPARGPPARDPPARAF7F3 | |
| SCHEMBL5379268 | 1.00 | PPARG (0.67) | PPARGPPARDPPARAF7F3 | |
| SCHEMBL28304955 | 1.00 | PPARG (0.67) | PPARGPPARDPPARAF7F3 | |
| SCHEMBL16308004 | 1.00 | PPARG (0.67) | PPARGPPARDPPARAF7F3 | |
| SCHEMBL20197662 | 1.00 | PPARG (0.67) | PPARGPPARDPPARAF7F3 | |
| SCHEMBL16523047 | 1.00 | PPARG (0.67) | PPARGPPARDPPARAF7F3 | |
| SCHEMBL15320686 | 1.00 | PPARG (0.67) | PPARGPPARDPPARAF7F3 | |
| SCHEMBL8984377 | 0.98 | PPARG (0.63) | PPARGPPARDPPARAF7F3 | |
| SCHEMBL8327969 | 0.98 | PPARG (0.63) | PPARGPPARDPPARAF7F3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118459485-A | Amino-substituted heterocycles for the treatment of cancers with EGFR mutations | 纽威伦特公司 | 2024-08-09 | — | — | CN | disclosed |
| CN-117500803-A | Amino-substituted heterocycles for the treatment of cancers with EGFR mutations | 纽威伦特公司 | 2024-02-02 | — | — | CN | disclosed |
| CN-116546986-A | ALK-5 inhibitors and uses thereof | 住友制药肿瘤公司 | 2023-08-04 | — | — | CN | disclosed |
| US-10906861-B2 | Methods of making organic compounds by metathesis | WILMAR TRADING PTE LTD (SG) | 2021-02-02 | — | — | US | disclosed |
| US-10087137-B2 | Cross metathesis approach to C11-C13 fatty-chain amino esters from oleic acid derivatives | THE UNIVERSITY OF TOLEDO (US) | 2018-10-02 | — | — | US | disclosed |
| EP-3281931-A1 | METHODS OF MAKING ORGANIC COMPOUNDS BY METATHESIS | Elevance Renewable Sciences, Inc. (US) | 2018-02-14 | — | — | EP | disclosed |
| US-20170204051-A1 | Cross Metathesis Approach to C11-C13 Fatty-Chain Amino Esters From Oleic Acid Derivatives | THE UNIVERSITY OF TOLEDO (US) | 2017-07-20 | — | — | US | disclosed |
| EP-3008078-A1 | CATALYSTS FOR EFFICIENT Z-SELECTIVE METATHESIS | Trustees of Boston College (US) | 2016-04-20 | — | — | EP | disclosed |
| WO-2015200200-A1 | CROSS METATHESIS APPROACH TO C11-C13 FATTY-CHAIN AMINO ESTERS FORM OLEIC ACID DERIVATIVES | THE UNIVERSITY OF TOLEDO (US) | 2015-12-30 | — | — | WO | disclosed |
| US-20150307438-A1 | Methods of Making Organic Compounds by Metathesis | ELEVANCE RENEWABLE SCIENCES, INC. (US) | 2015-10-29 | — | — | US | disclosed |
| US-9120742-B2 | Methods of making organic compounds by metathesis | ELEVANCE RENEWABLE SCIENCES, INC. (US) | 2015-09-01 | — | — | US | disclosed |
| WO-2014201300-A1 | CATALYSTS FOR EFFICIENT Z-SELECTIVE METATHESIS | TRUSTEES OF BOSTON COLLEGE (US) | 2014-12-18 | — | — | WO | disclosed |
| US-20090264672-A1 | METHODS OF MAKING ORGANIC COMPOUNDS BY METATHESIS | ELEVANCE RENEWABLE SCIENCES, INC. (US) | 2009-10-22 | — | — | US | disclosed |
| US-7247697-B2 | Coating compositions for use in golf balls | ACUSHNET COMPANY (US) | 2007-07-24 | — | — | US | disclosed |
| US-20060089419-A1 | Coating compositions for use in golf balls | JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT | 2006-04-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090264672-A1 | METHODS OF MAKING ORGANIC COMPOUNDS BY METATHESIS | COASY, FASN, HAO2 | PPARG 1388/4885PPARD 352/4885PPARA 879/4885 |
| US-10906861-B2 | Methods of making organic compounds by metathesis | COASY, FASN, HAO2 | PPARG 1388/4885PPARD 352/4885PPARA 879/4885 |
| US-20150307438-A1 | Methods of Making Organic Compounds by Metathesis | COASY, FASN, HAO2 | PPARG 1388/4885PPARD 352/4885PPARA 879/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.