⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16091005 | 0.67 | — | — | |
| SCHEMBL1276796 | 0.57 | — | — | |
| SCHEMBL15364669 | 0.57 | — | — | |
| SCHEMBL3314288 | 0.57 | — | — | |
| SCHEMBL14022719 | 0.56 | — | — | |
| SCHEMBL2418813 | 0.54 | CHRM2 (0.31) | — | |
| SCHEMBL11868831 | 0.54 | TSHR (0.31) | — | |
| SCHEMBL4166487 | 0.54 | — | — | |
| SCHEMBL25348867 | 0.54 | — | — | |
| Bromide SCHEMBL9458205 | 0.53 | CHRM2 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121654-A1 | 5-PYRIDINONE SUBSTITUTED INDAZOLES | Albany Molecular Research, Inc. (US) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008086404-A1 | 5-PYRIDINONE SUBSTITUTED INDAZOLES | ALBANY MOLECULAR RESEARCH, INC. (US) | 2008-07-17 | — | — | WO | disclosed |