SCHEMBL4450393

SCHEMBL4450393

ON=C1N=CC=N1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31494129 0.64
SCHEMBL2394640 0.58
SCHEMBL11204917 0.48
SCHEMBL186926 0.48
SCHEMBL2704746 0.48
SCHEMBL93568 0.48 HSP90AA1 (0.33)
SCHEMBL4613608 0.44
SCHEMBL553654 0.40
SCHEMBL325170 0.40
SCHEMBL12992748 0.36

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115536589-B Imidazolone oxime ester compound, preparation method, composition and application 江苏裕事达新材料科技有限责任公司 2024-11-22 CN claimed
CN-109694352-B Imidazole ketoxime ester compound, preparation method, composition and application 江苏裕事达新材料科技有限责任公司 2023-04-07 CN claimed
CN-115536589-A Imidazole ketoxime ester compound, preparation method, composition and application 江苏裕事达新材料科技有限责任公司 2022-12-30 CN claimed
CN-115536589-B Imidazolone oxime ester compound, preparation method, composition and application 江苏裕事达新材料科技有限责任公司 2024-11-22 CN disclosed
CN-115536589-B Imidazolone oxime ester compound, preparation method, composition and application 江苏裕事达新材料科技有限责任公司 2024-11-22 CN disclosed
CN-115536589-B Imidazolone oxime ester compound, preparation method, composition and application 江苏裕事达新材料科技有限责任公司 2024-11-22 CN disclosed
CN-109694352-B Imidazole ketoxime ester compound, preparation method, composition and application 江苏裕事达新材料科技有限责任公司 2023-04-07 CN disclosed
CN-109694352-B Imidazole ketoxime ester compound, preparation method, composition and application 江苏裕事达新材料科技有限责任公司 2023-04-07 CN disclosed
CN-115536589-A Imidazole ketoxime ester compound, preparation method, composition and application 江苏裕事达新材料科技有限责任公司 2022-12-30 CN disclosed
CN-115536589-A Imidazole ketoxime ester compound, preparation method, composition and application 江苏裕事达新材料科技有限责任公司 2022-12-30 CN disclosed
CN-110437107-B Acrylketoxime ester compound, preparation method and composition 江苏裕事达新材料科技有限责任公司 2022-11-08 CN disclosed
CN-108137507-A Proteolysis conditioning agent and relevant application method based on MDM2 阿尔维纳斯股份有限公司 2018-06-08 CN disclosed
CN-108136044-A Imide-based proteolytic modulators and related methods of use 阿尔维纳斯股份有限公司 2018-06-08 CN disclosed
CN-107382871-A The synthetic method of cyazofamid 无锡市稼宝药业有限公司 2017-11-24 CN disclosed
US-8198461-B2 Process for the preparation of 3-cyano-1,2,4-triazoles AMPAC FINE CHEMICALS LLC. (US) 2012-06-12 US disclosed
US-20090292122-A1 PROCESS FOR THE PREPARATION OF CYANO-SUBSTITUTED-NITROGEN-CONTAINING HETEROARYL COMPOUNDS AMPAC FINE CHEMICALS LLC (US) 2009-11-26 US disclosed
WO-2009137742-A1 PROCESS FOR THE PREPARATION OF CYANO-SUBSTITUTED-NITROGEN-CONTAINING HETEROARYL COMPOUNDS AMPAC FINE CHEMICALS LLC (US) 2009-11-12 WO disclosed