⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7548179 | 0.89 | — | — | |
| SCHEMBL12216619 | 0.87 | — | — | |
| SCHEMBL16325223 | 0.87 | — | — | |
| SCHEMBL9685316 | 0.85 | — | — | |
| SCHEMBL5452684 | 0.80 | LMNA (0.32) | — | |
| SCHEMBL1748587 | 0.78 | — | — | |
| SCHEMBL12313403 | 0.78 | — | — | |
| SCHEMBL5904940 | 0.78 | — | — | |
| SCHEMBL4135098 | 0.78 | TSHR (0.30) | — | |
| SCHEMBL10858660 | 0.78 | TSHR (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1603930-B1 | PROTEIN-BOUND DERIVATIVES OF PLATINUM COMPLEXES CONTAINING CYCLOBUTANE 1.1-DICARBOXYLLATE LIGANDS | KTB TUMORFORSCHUNGS GMBH (DE) | 2007-08-29 | — | — | EP | claimed |
| US-7141691-B2 | Protein-bound derivatives of platinum complexes containing cyclobutane1, 1-dicarboxyllate ligands | KTB TUMORFORSCHUNGS GMBH (DE) | 2006-11-28 | — | — | US | claimed |
| US-20060089341-A1 | Protein-bound derivatives of platinum complexes containing cyclobutane1,1-dicarboxyllate ligands | KTB TUMORFORSCHUNGS GMBH (DE) | 2006-04-27 | — | — | US | claimed |
| EP-4747258-A2 | COMPOUNDS, COMPOSITIONS, AND METHODS | Tenvie Therapeutics, Inc. (US) | 2026-05-27 | — | — | EP | disclosed |
| WO-2025076632-A1 | COMPOUNDS AND USES THEREOF | FIBROCOR THERAPEUTICS INC. (CA) | 2025-04-17 | — | — | WO | disclosed |
| WO-2025024329-A2 | COMPOUNDS, COMPOSITIONS, AND METHODS | NICO THERAPEUTICS, INC. (US) | 2025-01-30 | — | — | WO | disclosed |
| CN-115427410-B | Amide or sulfonamide derivatives and application thereof | 苏州恩华生物医药科技有限公司 | 2024-02-23 | — | — | CN | disclosed |
| CN-116425678-A | Hydrochloride of aminocyclobutane derivative and crystal form and preparation thereof | 苏州恩华生物医药科技有限公司 | 2023-07-14 | — | — | CN | disclosed |
| CN-116425677-A | Salts of aminocyclobutane derivatives, crystalline forms thereof, and preparation methods and applications thereof | 苏州恩华生物医药科技有限公司 | 2023-07-14 | — | — | CN | disclosed |
| CN-114269747-B | 1',2' -dihydro-3'H-spiro [ cyclobutane 1,4' -isoquinoline ] -3' -one derivative and application thereof | 苏州恩华生物医药科技有限公司 | 2023-04-18 | — | — | CN | disclosed |
| US-20230081390-A1 | INHIBITORS OF RAF KINASES | Pierre Fabre Médicament (FR) | 2023-03-16 | — | — | US | disclosed |
| US-20060183742-A1 | Pyrazolidine-1,2-dicarboxyldiphenylamide derivatives as coagulation factor xa inhibitors for the treatment of thromboses | MERCK PATENT GMBH (DE) | 2006-08-17 | — | — | US | disclosed |
| US-20060089341-A1 | Protein-bound derivatives of platinum complexes containing cyclobutane1,1-dicarboxyllate ligands | KTB TUMORFORSCHUNGS GMBH (DE) | 2006-04-27 | — | — | US | disclosed |
| EP-1608645-A1 | PYRAZOLIDINE-1,2-DICARBOXYLDIPHENYLAMIDE DERIVATIVES AS COAGULATION FACTOR XA INHIBITORS FOR THE TREATMENT OF THROMBOSES | MERCK PATENT GmbH (DE) | 2005-12-28 | — | — | EP | disclosed |
| EP-1395259-A4 | URAZOLE COMPOUNDS USEFUL AS ANTI-INFLAMMATORY AGENTS | BRISTOL MYERS SQUIBB CO (US) | 2005-01-26 | — | — | EP | disclosed |
| WO-2004087696-A1 | PYRAZOLIDINE-1,2-DICARBOXYLDIPHENYLAMIDE DERIVATIVES AS COAGULATION FACTOR XA INHIBITORS FOR THE TREATMENT OF THROMBOSES | MERCK PATENT GMBH (DE) | 2004-10-14 | — | — | WO | disclosed |
| EP-1395259-A2 | URAZOLE COMPOUNDS USEFUL AS ANTI-INFLAMMATORY AGENTS | Bristol-Myers Squibb Company (US) | 2004-03-10 | — | — | EP | disclosed |
| US-6673825-B2 | ANTIINFLAMMATORY AGENTS; IMMUNOSUPPRESSANTS | BRISTOL-MYERS SQUIBB CO. | 2004-01-06 | — | — | US | disclosed |
| US-20030013745-A1 | Urazole compounds useful as anti-inflammatory agents | CEREP SA (FR) | 2003-01-16 | — | — | US | disclosed |
| WO-2002094186-A2 | URAZOLE COMPOUNDS USEFUL AS ANTI-INFLAMMATORY AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2002-11-28 | — | — | WO | disclosed |