Known targets — ChEMBL curated mechanism
PPARDPTGS1PTGS2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Lysine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.48 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 7/20 | 0.36 |
| ▸ | DPP4 | P27487 | 4/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.36 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.35 |
| ▸ | FAP | Q12884 | 1/20 | 0.34 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.33 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.33 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.33 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.33 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.33 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lysine SCHEMBL20641479 | 1.00 | GSR (0.48) | GSRSLC7A5DPP7DPP4DPP8 | |
| Lysine SCHEMBL29253065 | 1.00 | GSR (0.48) | GSRSLC7A5DPP7DPP4DPP8 | |
| Lysine SCHEMBL5575951 | 0.91 | GSR (0.51) | GSRDPP7DPP4DPP8DPP9 | |
| Lysine SCHEMBL29069496 | 0.91 | GSR (0.51) | GSRDPP7DPP4DPP8DPP9 | |
| Lysine SCHEMBL1675274 | 0.91 | GSR (0.51) | GSRDPP7DPP4DPP8DPP9 | |
| Lysine SCHEMBL23834597 | 0.91 | GSR (0.57) | GSRDPP7DPP4DPP8DPP9 | |
| Lysine SCHEMBL1696608 | 0.91 | GSR (0.57) | GSRDPP7DPP4DPP8DPP9 | |
| Lysine SCHEMBL4296375 | 0.91 | GSR (0.57) | GSRDPP7DPP4DPP8DPP9 | |
| Lysine SCHEMBL1537262 | 0.91 | GSR (0.57) | GSRDPP7DPP4DPP8DPP9 | |
| Lysine SCHEMBL11660661 | 0.91 | GSR (0.57) | GSRDPP7DPP4DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090298773-A1 | METHODS OF PRODUCING FUNCTIONAL MISO | MARUKOME CO., LTD. (JP) | 2009-12-03 | — | — | US | disclosed |