Known targets — ChEMBL curated mechanism
PPARDPTGS1PTGS2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Lysine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.51 |
| ▸ | DPP7 | Q9UHL4 | 7/20 | 0.38 |
| ▸ | DPP4 | P27487 | 4/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.38 |
| ▸ | FAP | Q12884 | 1/20 | 0.36 |
| ▸ | ARG1 | P05089 | 3/20 | 0.35 |
| ▸ | ARG2 | P78540 | 3/20 | 0.35 |
| ▸ | NOS3 | P29474 | 2/20 | 0.35 |
| ▸ | NOS1 | P29475 | 2/20 | 0.35 |
| ▸ | NOS2 | P35228 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lysine SCHEMBL29069496 | 1.00 | GSR (0.51) | GSRDPP7DPP4DPP8DPP9 | |
| Lysine SCHEMBL1675274 | 1.00 | GSR (0.51) | GSRDPP7DPP4DPP8DPP9 | |
| Lysine SCHEMBL18263286 | 0.96 | GSR (0.48) | GSRDPP7DPP4DPP8DPP9 | |
| Lysine SCHEMBL18259132 | 0.96 | GSR (0.48) | GSRDPP7DPP4DPP8DPP9 | |
| Lysine SCHEMBL17728306 | 0.95 | GSR (0.47) | GSRDPP7DPP4DPP8DPP9 | |
| Lysine SCHEMBL23834597 | 0.95 | GSR (0.57) | GSRDPP7DPP4DPP8DPP9 | |
| Lysine SCHEMBL5227175 | 0.95 | GSR (0.57) | GSRDPP7DPP4DPP8DPP9 | |
| Lysine SCHEMBL4296375 | 0.95 | GSR (0.57) | GSRDPP7DPP4DPP8DPP9 | |
| Lysine SCHEMBL1696608 | 0.95 | GSR (0.57) | GSRDPP7DPP4DPP8DPP9 | |
| Lysine SCHEMBL11660661 | 0.95 | GSR (0.57) | GSRDPP7DPP4DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2958971-B1 | MULTI COMPONENT ADHESIVE FOR THE PREPARATION OF ADHESIVE HYDROGELS | FRAUNHOFER GES FORSCHUNG (DE) | 2018-07-11 | — | — | EP | claimed |
| US-20160130484-A1 | MULTI-COMPONENT ADHESIVE FOR PRODUCING AN ADHESIVE HYDROGEL | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) | 2016-05-12 | — | — | US | claimed |
| CN-117580584-A | Peptide modified nanoparticles for enrichment of specific protein subsets | 禧尔公司 | 2024-02-20 | — | — | CN | disclosed |
| US-20160130484-A1 | MULTI-COMPONENT ADHESIVE FOR PRODUCING AN ADHESIVE HYDROGEL | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) | 2016-05-12 | — | — | US | disclosed |
| US-7276341-B2 | Octapeptides for detection and treatment of autoimmune disorders | OKLAHOMA MEDICAL RESEARCH FOUNDATION (US) | 2007-10-02 | — | — | US | disclosed |
| US-6897287-B1 | Ro/SSA peptide reagents for diagnosis of autoantibodies | OKLAHOMA MEDICAL RESEARCH FOUNDATION (US) | 2005-05-24 | — | — | US | disclosed |
| US-20030216544-A1 | Methods and reagents for diagnosis of autoantibodies | BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA | 2003-11-20 | — | — | US | disclosed |
| US-6641813-B1 | Octapeptides were generated from the sequences encoding the 60 kDa Ro/SSA peptide, the La/SSB autoantigen, the 70 kD nuclear ribonucleoprotein (nRNP), and the Sm B/B' polypeptide, which represent linear epitopes for autoantibodies presence of blood | OKLAHOMA MEDICAL RESEARCH FOUNDATION | 2003-11-04 | — | — | US | disclosed |
| EP-0640101-B1 | METHODS AND REAGENTS FOR DIAGNOSIS OF AUTOANTIBODIES | OKLAHOMA MED RES FOUND (US) | 1999-12-08 | — | — | EP | disclosed |
| EP-0640101-A4 | METHODS AND REAGENTS FOR DIAGNOSIS OF AUTOANTIBODIES. | UNIV OKLAHOMA STATE (US) | 1995-06-21 | — | — | EP | disclosed |
| EP-0640101-A1 | METHODS AND REAGENTS FOR DIAGNOSIS OF AUTOANTIBODIES | BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA (US) | 1995-03-01 | — | — | EP | disclosed |
| WO-1993021223-A1 | METHODS AND REAGENTS FOR DIAGNOSIS OF AUTOANTIBODIES | BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA (US) | 1993-10-28 | — | — | WO | disclosed |