SCHEMBL4450783

SCHEMBL4450783

CC(C)(c1ccc(O)cc1)c1ccc(Oc2ccc(C(C)(C)c3ccc(O)cc3)cc2)cc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 4/20 0.73
ESR2 Q92731 4/20 0.73
CYP3A4 P08684 2/20 0.73
HPGD P15428 2/20 0.73
AR P10275 1/20 0.73
TSHR P16473 1/20 0.73
SLC6A2 P23975 1/20 0.73
SLC6A4 P31645 1/20 0.73
HTR6 P50406 1/20 0.73
ESRRG P62508 1/20 0.73
SLC6A3 Q01959 1/20 0.73
HSD17B10 Q99714 1/20 0.73
MEN1 O00255 2/20 0.64
KMT2A Q03164 2/20 0.64
ALDH1A1 P00352 2/20 0.61
LTA4H P09960 6/20 0.58
NR1H2 P55055 1/20 0.54
BAX Q07812 1/20 0.54
LMNA P02545 1/20 0.52
TYR P14679 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10865719 1.00 ESR1 (0.73) ESR1ESR2CYP3A4HPGDAR
SCHEMBL21360606 0.94 ESR1 (0.64) ESR1ESR2CYP3A4HPGDAR
SCHEMBL12994049 0.92 ESR1 (0.70) ESR1ESR2CYP3A4HPGDAR
Bisphenol A SCHEMBL2463040 0.90 ESR1 (0.73) ESR1ESR2CYP3A4HPGDAR
SCHEMBL11225969 0.89 ESR2 (0.70) ESR1ESR2CYP3A4HPGDAR
SCHEMBL13326876 0.89 ESR1 (0.61) ESR1ESR2CYP3A4HPGDAR
SCHEMBL24437034 0.87 ESR1 (0.59) ESR1ESR2CYP3A4HPGDAR
SCHEMBL12890394 0.87 ELANE (0.60) ESR1ESR2CYP3A4HPGDAR
SCHEMBL13347335 0.87 ELANE (0.60) ESR1ESR2CYP3A4HPGDAR
SCHEMBL3148686 0.86 LMNA (0.73) ESR1ESR2CYP3A4HPGDAR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 142 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0379058-B1 Vinyl ester resins containing mesogenic/rigid rodlike moieties DOW CHEMICAL CO (US) 1999-09-29 EP claimed
US-5342904-A Polymer modified adducts of epoxy resins and active hydrogen containing compounds containing mesogenic moieties THE DOW CHEMICAL COMPANY (US) 1994-08-30 US claimed
US-5235008-A Curable THE DOW CHEMICAL COMPANY (US) 1993-08-10 US claimed
US-5164464-A Liquid crystalline polymers, acrylated epoxy resins THE DOW CHEMICAL COMPANY (US) 1992-11-17 US claimed
US-4962163-A ADVANCED POLYEPOXIDES AND EPOXY RESINS MODIFIED BY AN UNSATURATED CARBOXYLIC ACID; CURED COATING AND FILMS HAVINGI IMPROVED TENSILE AND FLEXURAL STRENGTH AND MODULUS THE DOW CHEMICAL COMPANY (US) 1990-10-09 US claimed
EP-0379058-A2 Vinyl ester resins containing mesogenic/rigid rodlike moieties THE DOW CHEMICAL COMPANY (US) 1990-07-25 EP claimed
US-9670315-B2 Polycarbonate resin composition, and fluorescence detection/analysis substrate produced using polycarbonate resin composition MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2017-06-06 US disclosed
US-9670315-B2 Polycarbonate resin composition, and fluorescence detection/analysis substrate produced using polycarbonate resin composition MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2017-06-06 US disclosed
US-20160152768-A1 POLYCARBONATE RESIN COMPOSITION, AND FLUORESCENCE DETECTION/ANALYSIS SUBSTRATE PRODUCED USING POLYCARBONATE RESIN COMPOSITION MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2016-06-02 US disclosed
US-20160152768-A1 POLYCARBONATE RESIN COMPOSITION, AND FLUORESCENCE DETECTION/ANALYSIS SUBSTRATE PRODUCED USING POLYCARBONATE RESIN COMPOSITION MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2016-06-02 US disclosed
US-9354356-B2 Polymer film, and optically-compensatory film, polarizer and liquid-crystal display device comprising the same FUJIFILM CORPORATION (JP) 2016-05-31 US disclosed
US-9354356-B2 Polymer film, and optically-compensatory film, polarizer and liquid-crystal display device comprising the same FUJIFILM CORPORATION (JP) 2016-05-31 US disclosed
US-9091804-B2 Polymer film, and optically-compensatory film, polarizer and liquid-crystal display device comprising the same FUJIFILM CORPORATION (JP) 2015-07-28 US disclosed
US-4487915-A CASTINGS, COATINGS, LAMINATION THE DOW CHEMICAL COMPANY (US) 1984-12-11 US disclosed
US-4094861-A Process for the production of non-inflammable polytriazines BAYER AKTIENGESELLSCHAFT (DT) 1978-06-13 US disclosed
US-4049630-A Process for preparation of s-triazine prepolymers BAYER AKTIENGESELLSCHAFT (DT) 1977-09-20 US disclosed
US-4046796-A Process for the production of polyfunctional cyanic acid esters BAYER AKTIENGESELLSCHAFT (DT) 1977-09-06 US disclosed
US-4042567-A S-Triazine prepolymers and a process for their production BAYER AKTIENGESELLSCHAFT (DT) 1977-08-16 US disclosed
US-4028393-A Process for the production of polyfunctional cyanic acid esters BAYER AKTIENGESELLSCHAFT (DT) 1977-06-07 US disclosed
US-3978028-A Process for preparing s-triazine prepolymers by condensation of an aromatic polyhydroxy compound with cyanuric chloride and thereafter reacting the condensation product with cyanogen halide in the presence of base BAYER AKTIENGESELLSCHAFT (DT) 1976-08-31 US disclosed