Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.71 |
| ▸ | CES1 | P23141 | 3/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.64 |
| ▸ | MAPT | P10636 | 4/20 | 0.64 |
| ▸ | NPC1 | O15118 | 6/20 | 0.63 |
| ▸ | RAB9A | P51151 | 6/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | STAT3 | P40763 | 1/20 | 0.63 |
| ▸ | STAT1 | P42224 | 1/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.53 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.53 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzophenone SCHEMBL25224295 | 0.94 | ALDH1A1 (0.67) | CES2CES1SMN1; SMN2MAPTNPC1 | |
| Acetophenone SCHEMBL16333594 | 0.93 | SMN1; SMN2 (0.60) | CES2CES1SMN1; SMN2MAPTNPC1 | |
| Acetophenone SCHEMBL27586437 | 0.91 | SMN1; SMN2 (0.58) | CES2CES1SMN1; SMN2MAPTNPC1 | |
| SCHEMBL721041 | 0.90 | SMN1; SMN2 (0.74) | CES2CES1SMN1; SMN2MAPTNPC1 | |
| SCHEMBL55409 | 0.90 | SMN1; SMN2 (0.74) | CES2CES1SMN1; SMN2MAPTNPC1 | |
| Toluene SCHEMBL27465391 | 0.89 | ALDH1A1 (0.60) | CES2CES1SMN1; SMN2MAPTNPC1 | |
| Bromide SCHEMBL28439252 | 0.87 | SMN1; SMN2 (0.71) | CES2CES1SMN1; SMN2MAPTNPC1 | |
| Acetophenone SCHEMBL737 | 0.87 | — | — | |
| Acetophenone SCHEMBL30537000 | 0.87 | — | — | |
| Acetophenone SCHEMBL16745259 | 0.87 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065430-A1 | Application of Metal Amidoborane and Their Derivatives in Reduction Reaction | DALIAN INSTITUTE OF CHEMICAL PHYSICS, CHINESE ACADEMY OF SCIENCES (CN) | 2012-03-15 | — | — | US | claimed |
| CN-109046463-A | Bidentate azepine Cabbeen Mn catalyst and preparation method thereof and alkylation synthesis application | 中山大学 | 2018-12-21 | — | — | CN | disclosed |
| US-20120065430-A1 | Application of Metal Amidoborane and Their Derivatives in Reduction Reaction | DALIAN INSTITUTE OF CHEMICAL PHYSICS, CHINESE ACADEMY OF SCIENCES (CN) | 2012-03-15 | — | — | US | disclosed |
| EP-1954796-A1 | IMPROVEMENTS RELATING TO FABRIC TREATMENT COMPOSITIONS | UNILEVER PLC (GB) | 2008-08-13 | — | — | EP | disclosed |
| WO-2007062833-A1 | IMPROVEMENTS RELATING TO FABRIC TREATMENT COMPOSITIONS | UNILEVER PLC (GB) | 2007-06-07 | — | — | WO | disclosed |