Phthalic Acid

Phthalic Acid

SCHEMBL4451020

COCCCO.O=C(O)c1ccccc1C(=O)O

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.52
ALOX15 P16050 1/20 0.52
MAPK1 P28482 1/20 0.51
TSHR P16473 1/20 0.50
HTT P42858 3/20 0.49
KMT2A Q03164 4/20 0.45
HPGD P15428 3/20 0.45
HSD17B10 Q99714 3/20 0.45
USP2 O75604 1/20 0.45
TP53 P04637 1/20 0.45
TDP1 Q9NUW8 2/20 0.44
POLB P06746 1/20 0.44
KDM4E B2RXH2 2/20 0.43
APEX1 P27695 1/20 0.43
PTK2B Q14289 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phthalic Acid SCHEMBL27719965 0.89 ALDH1A1 (0.56) ALDH1A1ALOX15MAPK1TSHRHTT
Phthalic Acid SCHEMBL81888 0.86 TSHR (0.64) ALDH1A1ALOX15MAPK1TSHRHTT
Phthalic Acid SCHEMBL31495206 0.86 TSHR (0.64) ALDH1A1ALOX15MAPK1TSHRHTT
Phthalic Acid SCHEMBL27744826 0.82 KDM4E (0.49) ALDH1A1ALOX15TSHRHTTKMT2A
Phthalic Acid SCHEMBL7203558 0.82 ALDH1A1 (0.70) ALDH1A1ALOX15HTTKMT2AHPGD
Phthalic Acid SCHEMBL27790612 0.82 ALDH1A1 (0.70) ALDH1A1ALOX15TSHRHTTKMT2A
Phthalic Acid SCHEMBL10360600 0.82 ALDH1A1 (0.70) ALDH1A1ALOX15HTTKMT2AHPGD
Phthalic Acid SCHEMBL27697914 0.81 ALDH1A1 (0.56) ALDH1A1ALOX15MAPK1TSHRHTT
Phthalic Acid SCHEMBL9804564 0.81 ALDH1A1 (0.59) ALDH1A1ALOX15MAPK1TSHRHTT
SCHEMBL28117434 0.81 TSHR (0.69) ALDH1A1ALOX15MAPK1TSHRKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180264019-A1 COMPOSITION, DEVICE AND METHOD FOR DELAYED AND SUSTAINED RELEASE OF BRAIN ENERGY MOLECULES ABLE CEREBRAL, LLC 2018-09-20 US claimed
US-10016370-B2 Composition, device and method for delayed and sustained release of brain energy molecules ABLE CEREBRAL, LLC (US) 2018-07-10 US claimed
CN-101453990-B Bupropion controllable release formulations and manufacturing process thereof BIOKEY INC 2015-05-13 CN claimed
CN-103945832-A A composition, device and method for delayed and sustained release of brain energy molecules JACKS HEALTH TECHNOLOGIES LLC 2014-07-23 CN claimed
US-20140180224-A1 COMPOSITION, DEVICE AND METHOD FOR DELAYED AND SUSTAINED RELEASE OF BRAIN ENERGY MOLECULES ABLE CEREBRAL, LLC 2014-06-26 US claimed
EP-2731593-A2 A COMPOSITION, DEVICE AND METHOD FOR DELAYED AND SUSTAINED RELEASE OF BRAIN ENERGY MOLECULES Able Cerebral, LLC (US) 2014-05-21 EP claimed
US-8586085-B2 Methods and formulations for making pharmaceutical compositions containing bupropion BIOKEY, INC. (US) 2013-11-19 US claimed
WO-2013010137-A2 A COMPOSITION, DEVICE AND METHOD FOR DELAYED AND SUSTAINED RELEASE OF BRAIN ENERGY MOLECULES JACKS HEALTH TECHNOLOGIES LLC (US) 2013-01-17 WO claimed
CN-102475719-A A pharmaceutical composition for treating upper respiratory infection of children, and its preparation method SHINEWAY PHARMACEUTICAL CO LTD 2012-05-30 CN claimed
US-20090162431-A1 Sustained release formulations containing acetaminophen and tramadol ZHANG SHUYI 2009-06-25 US claimed
WO-2006053089-A2 METHODS AND FORMULATIONS FOR MAKING PHARMACEUTICAL COMPOSITIONS CONTAINING BUPROPION BIOKEY, INC. (US) 2006-05-18 WO claimed
US-20060099260-A1 Methods and formulations for making pharmaceutical compositions containing bupropion BIOKEY, INC. 2006-05-11 US claimed
US-20060099262-A1 Methods and formulations for making controlled release oral dosage form BIOKEY, INC. 2006-05-11 US claimed
US-20060099261-A1 Methods and formulations for making controlled release oral dosage form BIOKEY, INC. 2006-05-11 US claimed
EP-1555022-A1 SUSTAINED RELEASE COMPOUND OF ACETAMIDOPHENOL AND TRAMADOL Zhang, Shugi (CN) 2005-07-20 EP claimed
US-20040131671-A1 Sustained release formulations containing acetaminophen and tramadol ZHANG SHUYI (US) 2004-07-08 US claimed
CN-1403078-A Slow-releasing prepn containing p-acetamidophenol and opium SHANGHAI YAHU PHARMACEUTICAL C (CN) 2003-03-19 CN claimed
EP-1035840-A1 SUSTAINED RELEASE FORMULATION CONTAINING THREE DIFFERENT TYPES OF POLYMERS AND TABLET FORMED THEREFROM Duramed Pharmaceuticals Inc. (US) 2000-09-20 EP claimed
US-6083532-A TABLETS FOR SUSTAINED RELEASE OF DRUGS AND GELLING POLYMER DURAMED PHARMACEUTICALS, INC. (US) 2000-07-04 US claimed
WO-1999029305-A1 SUSTAINED RELEASE FORMULATION CONTAINING THREE DIFFERENT TYPES OF POLYMERS AND TABLET FORMED THEREFROM DURAMED PHARMACEUTICALS, INC. (US) 1999-06-17 WO claimed