Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNFRSF1A | P19438 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | TACR3 | P29371 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | GPR139 | Q6DWJ6 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4451029 | 1.00 | TNFRSF1A (0.48) | TNFRSF1AALDH1A1S1PR3RXFP1TACR3 | |
| SCHEMBL4457047 | 1.00 | TNFRSF1A (0.48) | TNFRSF1AALDH1A1S1PR3RXFP1TACR3 | |
| SCHEMBL4447518 | 0.87 | TNFRSF1A (0.47) | TNFRSF1AALDH1A1S1PR3RXFP1TACR3 | |
| SCHEMBL4450275 | 0.87 | TNFRSF1A (0.47) | TNFRSF1AALDH1A1S1PR3RXFP1TACR3 | |
| SCHEMBL4447516 | 0.87 | TNFRSF1A (0.47) | TNFRSF1AALDH1A1S1PR3RXFP1TACR3 | |
| SCHEMBL4449921 | 0.86 | TNFRSF1A (0.46) | TNFRSF1AALDH1A1S1PR3RXFP1TACR3 | |
| SCHEMBL4449926 | 0.86 | TNFRSF1A (0.46) | TNFRSF1AALDH1A1S1PR3RXFP1TACR3 | |
| SCHEMBL4446586 | 0.86 | TNFRSF1A (0.46) | TNFRSF1AALDH1A1RXFP1LMNAMEN1 | |
| SCHEMBL4446583 | 0.86 | TNFRSF1A (0.46) | TNFRSF1AALDH1A1RXFP1LMNAMEN1 | |
| SCHEMBL4450893 | 0.81 | CA1 (0.46) | S1PR3TACR3LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090012010-A1 | Amino acid derivatives as calcium channel blockers | NEUROMED PHRAMACEUTICALS LTD. (CA) | 2009-01-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090012010-A1 | Amino acid derivatives as calcium channel blockers | CACNA1G, CACNA1H, CACNA1I | TNFRSF1A 3963/4885ALDH1A1 2335/4885S1PR3 4723/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.