Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.32 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL156896 | 1.00 | ALDH1A1 (0.52) | ALDH1A1TSHRTHRBNPC1HPGD | |
| Bicarbonate SCHEMBL26656722 | 1.00 | ALDH1A1 (0.52) | ALDH1A1TSHRTHRBNPC1HPGD | |
| Bicarbonate SCHEMBL376795 | 0.89 | ALDH1A1 (0.62) | ALDH1A1TSHRTHRBNPC1HPGD | |
| SCHEMBL2497918 | 0.89 | — | — | |
| Bicarbonate SCHEMBL11500913 | 0.89 | ALDH1A1 (0.62) | ALDH1A1TSHRTHRBNPC1HPGD | |
| SCHEMBL17953585 | 0.86 | ALDH1A1 (0.50) | ALDH1A1TSHRTHRBEPHX2 | |
| Bicarbonate SCHEMBL30051784 | 0.86 | ALDH1A1 (0.59) | ALDH1A1TSHRTHRBNPC1HPGD | |
| Bicarbonate SCHEMBL377470 | 0.86 | ALDH1A1 (0.59) | ALDH1A1TSHRTHRBNPC1HPGD | |
| Bicarbonate SCHEMBL6272395 | 0.81 | ALDH1A1 (0.54) | ALDH1A1TSHRTHRBNPC1HPGD | |
| SCHEMBL9245893 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 195 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0191875-A1 | Process for preparation of polyvinyl chloride type polymer | Tosoh Corporation (JP) | 1986-08-27 | — | — | EP | claimed |
| CN-118355077-A | Resin composition, laminate, prepreg, cured product, substrate with cured product, and electronic device | 爱天思株式会社 | 2024-07-16 | — | — | CN | disclosed |
| CN-118339213-A | Thermosetting composition, adhesive sheet, printed wiring board, and electronic device | 爱天思株式会社 | 2024-07-12 | — | — | CN | disclosed |
| CN-118284635-A | Photocurable resin composition, fuel cell, and sealing method | 三键有限公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-107216821-B | Double-sided adhesive sheet, display, and method for manufacturing display | 琳得科株式会社 | 2024-06-25 | — | — | CN | disclosed |
| CN-118222091-A | Resin composition, laminate, prepreg, cured product, substrate with cured product, and electronic device | 爱天思株式会社 | 2024-06-21 | — | — | CN | disclosed |
| CN-118234820-A | Adhesive sheet and display | 琳得科株式会社 | 2024-06-21 | — | — | CN | disclosed |
| CN-118085742-A | Adhesive for flexible display, adhesive sheet, flexible laminate member, and flexible display | 琳得科株式会社 | 2024-05-28 | — | — | CN | disclosed |
| CN-118085741-A | Adhesive for flexible display, adhesive sheet, flexible laminate member, and flexible display | 琳得科株式会社 | 2024-05-28 | — | — | CN | disclosed |
| CN-118048117-A | Adhesive for repeated bending device, adhesive sheet, repeated bending laminated member, and repeated bending device | 琳得科株式会社 | 2024-05-17 | — | — | CN | disclosed |
| US-20070287644-A1 | LUBRICATING OIL COMPOSITION | SHELL OIL COMPANY | 2007-12-13 | — | — | US | disclosed |
| EP-1860175-A2 | Lubricating oil composition | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 2007-11-28 | — | — | EP | disclosed |
| EP-0658943-B1 | SOLAR CELL MODULE HAVING EXCELLENT WEATHER RESISTANCE | CANON KK (JP) | 2006-08-30 | — | — | EP | disclosed |
| EP-0950923-B1 | PHOTOSENSITIVE RESIN COMPOSITION AND FLEXOGRAPHIC RESIN PLATE | TOKYO OHKA KOGYO CO LTD (JP) | 2006-04-19 | — | — | EP | disclosed |
| CN-1414593-A | Manufacturing method of dielectric paste and plasma display | TORAY INDUSTRIES (JP) | 2003-04-30 | — | — | CN | disclosed |
| EP-0989175-A1 | Thermosetting adhesive | NITTO DENKO CORPORATION (JP) | 2000-03-29 | — | — | EP | disclosed |
| US-5718772-A | FILLER IS MADE OF VINYLIDENE FLUORIDE COPOLYMER AND ACRYLIC RESIN; EXCELLENT HEAT/WEAR RESISTANCE; DESIRABLE PHOTOELECTRIC CONVERSION EFFICIENCY OVER A LONG PERIOD OF TIME | CANON KABUSHIKI KAISHA (JP) | 1998-02-17 | — | — | US | disclosed |
| US-5578141-A | Solar cell module having excellent weather resistance | CANON KABUSHIKI KAISHA (JP) | 1996-11-26 | — | — | US | disclosed |
| EP-0658943-A1 | SOLAR CELL MODULE HAVING EXCELLENT WEATHER RESISTANCE | CANON KABUSHIKI KAISHA (JP) | 1995-06-21 | — | — | EP | disclosed |
| EP-0191875-A1 | Process for preparation of polyvinyl chloride type polymer | Tosoh Corporation (JP) | 1986-08-27 | — | — | EP | disclosed |