Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | LCLAT1 | Q6UWP7 | 5/20 | 0.40 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 6/20 | 0.38 |
| ▸ | RAB9A | P51151 | 5/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4451212 | 1.00 | KDM4E (0.42) | KDM4ELCLAT1FGFR3KDRSMN1; SMN2 | |
| SCHEMBL4564936 | 0.89 | KDM4E (0.44) | KDM4ELCLAT1FGFR3KDRSMN1; SMN2 | |
| SCHEMBL4564938 | 0.89 | KDM4E (0.44) | KDM4ELCLAT1FGFR3KDRSMN1; SMN2 | |
| SCHEMBL13783917 | 0.80 | CNR1 (0.41) | FGFR3KDRSMN1; SMN2POLBALDH1A1 | |
| SCHEMBL4457335 | 0.78 | CNR1 (0.41) | FGFR3KDRSMN1; SMN2NPC1RAB9A | |
| SCHEMBL13783790 | 0.78 | CNR1 (0.41) | FGFR3KDRSMN1; SMN2NPC1RAB9A | |
| SCHEMBL4457337 | 0.78 | CNR1 (0.41) | FGFR3KDRSMN1; SMN2NPC1RAB9A | |
| SCHEMBL4458275 | 0.78 | CCR3 (0.47) | KDM4ESMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL13783977 | 0.78 | CCR3 (0.47) | KDM4ESMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL4458269 | 0.78 | CCR3 (0.47) | KDM4ESMN1; SMN2ALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009090548-A2 | 3-AZABICYCLO [3.1.0] HEXANE DERIVATIVES AS VANILLOID RECEPTOR LIGANDS | GLENMARK PHARMACEUTICALS, S.A. (US) | 2009-07-23 | — | — | WO | disclosed |