Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 1/20 | 0.47 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 4/20 | 0.39 |
| ▸ | DRD4 | P21917 | 4/20 | 0.39 |
| ▸ | HTR2A | P28223 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13783977 | 1.00 | CCR3 (0.47) | CCR3AURKBHDAC3HDAC1HDAC2 | |
| SCHEMBL4458275 | 1.00 | CCR3 (0.47) | CCR3AURKBHDAC3HDAC1HDAC2 | |
| SCHEMBL13783974 | 0.87 | CCR3 (0.51) | CCR3AURKBHDAC3HDAC1HDAC2 | |
| SCHEMBL13783971 | 0.84 | CASR (0.41) | CCR3CNR1ALDH1A1MAPTRAB9A | |
| SCHEMBL4451072 | 0.84 | CASR (0.41) | CCR3CNR1ALDH1A1MAPTRAB9A | |
| SCHEMBL4451883 | 0.84 | CASR (0.41) | CCR3CNR1ALDH1A1MAPTRAB9A | |
| SCHEMBL4449093 | 0.82 | ALDH1A1 (0.43) | HDAC3HDAC1HDAC2KDM4EALDH1A1 | |
| SCHEMBL4449096 | 0.82 | ALDH1A1 (0.43) | HDAC3HDAC1HDAC2KDM4EALDH1A1 | |
| SCHEMBL13783959 | 0.82 | ALDH1A1 (0.43) | HDAC3HDAC1HDAC2KDM4EALDH1A1 | |
| SCHEMBL13783917 | 0.81 | CNR1 (0.41) | CCR3CNR1ALDH1A1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009090548-A2 | 3-AZABICYCLO [3.1.0] HEXANE DERIVATIVES AS VANILLOID RECEPTOR LIGANDS | GLENMARK PHARMACEUTICALS, S.A. (US) | 2009-07-23 | — | — | WO | disclosed |