⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4451337 | 1.00 | — | — | |
| SCHEMBL1451307 | 0.87 | HCAR2 (0.48) | — | |
| SCHEMBL1451306 | 0.87 | HCAR2 (0.48) | — | |
| SCHEMBL10802267 | 0.85 | HCAR2 (0.46) | — | |
| SCHEMBL10962241 | 0.84 | HCAR2 (0.44) | — | |
| SCHEMBL11076851 | 0.84 | HCAR2 (0.44) | — | |
| SCHEMBL24861049 | 0.83 | HCAR2 (0.48) | — | |
| SCHEMBL25768 | 0.81 | — | — | |
| SCHEMBL25769 | 0.81 | — | — | |
| SCHEMBL29626505 | 0.81 | HCAR2 (0.57) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090326019-A1 | 3,4-BICYCLIC PYRROLIDINE ANTIVIRALS | ENANTA PHARMACEUTICALS, INC. | 2009-12-31 | — | — | US | disclosed |
| CN-101418028-A | Synthesis of beta-l-2-deoxy nucleosides | IDENIX CAYMAN LTD (VG) | 2009-04-29 | — | — | CN | disclosed |
| CN-100475831-C | Synthesis of beta-L-2' -deoxynucleosides | NOVARTIS AG (CH) | 2009-04-08 | — | — | CN | disclosed |
| CN-1842535-A | Synthesis of beta-L-2' -deoxynucleosides | IDENIX CAYMAN LTD (KY) | 2006-10-04 | — | — | CN | disclosed |
| CN-1039423-A | 2, the preparation method of 2-dehydration-1-(β-D-arabinofuranosyl adenin base) thymus pyrimidine | PFIZER (US) | 1990-02-07 | — | — | CN | disclosed |
| US-4524151-A | 7-Oxabicycloheptane thio ethers useful as cardiovascular agents | E. R. SQUIBB & SONS, INC. (US) | 1985-06-18 | — | — | US | disclosed |
| US-4092427-A | ANTICOAGULANTS, OXYTOCICS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1978-05-30 | — | — | US | disclosed |
| US-4048329-A | HYPERTENSIVE AGENTS, BRONCHODILATOR AGENTS, GASTROINTESTINAL DISORDERS, PROSTAGLANDINS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1977-09-13 | — | — | US | disclosed |
| US-4048328-A | HYPERTENSIVE AGENTS, BRONCHODILATOR AGENTS, GASTROINTESTINAL DISORDERS, PROSTAGLANDINS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1977-09-13 | — | — | US | disclosed |
| US-4007171-A | PROSTAGLANDIN | AMERICAN HOME PRODUCTS CORPORATION (US) | 1977-02-08 | — | — | US | disclosed |
| US-3987081-A | ALKYL DERIVATIVES OF PROSTANOIC ACIDS AND PREPARATION THEREOF | AMERICAN HOME PRODUCTS CORPORATION (US) | 1976-10-19 | — | — | US | disclosed |