SCHEMBL25768

SCHEMBL25768

COC(=O)/C=C/CBr

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25769 1.00
SCHEMBL13308198 1.00
SCHEMBL24861049 0.87 HCAR2 (0.48)
SCHEMBL3195050 0.84 NFE2L2 (0.50)
SCHEMBL3195047 0.84 NFE2L2 (0.50)
SCHEMBL24861055 0.82 NFE2L2 (0.48)
SCHEMBL4451337 0.81
SCHEMBL4451339 0.81
SCHEMBL1870774 0.78 HCAR2 (0.55)
SCHEMBL212257 0.78 HCAR2 (0.55)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1307 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4676477-A1 METHODS FOR THE PREPARATION AND DOSE REGIMENS FOR USE OF SSTR4 AGONISTS AND SALTS THEREOF ELI LILLY AND COMPANY (US) 2026-01-14 EP claimed
CN-119708027-A Method for preparing boronated carbonyl derivative 中国科学院大连化学物理研究所 2025-03-28 CN claimed
WO-2024191686-A1 METHODS FOR THE PREPARATION AND DOSE REGIMENS FOR USE OF SSTR4 AGONISTS AND SALTS THEREOF ELI LILLY AND COMPANY (US) 2024-09-19 WO claimed
US-20240307349-A1 METHODS FOR THE PREPARATION AND DOSE REGIMENS FOR USE OF SSTR4 AGONISTS AND SALTS THEREOF LILLY CO ELI (US) 2024-09-19 US claimed
US-20230118467-A1 COSMETIC OR PHARMACEUTICAL USE OF AVENANTHRAMIDE L SYMRISE AG (DE) 2023-04-20 US claimed
EP-4114353-A1 COSMETIC OR PHARMACEUTICAL USE OF AVENANTHRAMIDE L Symrise AG (DE) 2023-01-11 EP claimed
CN-115243670-A Cosmetic or pharmaceutical use of avenanthramide L 西姆莱斯股份公司 2022-10-25 CN claimed
EP-2948437-B1 APPROACH FOR SYNTHESIS OF CATECHINS EPIRIUM BIO INC (US) 2021-11-03 EP claimed
CN-109608334-B Method for synthesizing 4-methoxy methyl crotonate 盐城通海生物科技有限公司 2021-07-13 CN claimed
CN-110003159-A Synthesize the new method of catechin 斯法尔制药私人有限公司 2019-07-12 CN claimed
CN-1761644-A Synthesis of 4-amino-2-butenoyl chloride and its use in preparation of 3-cyanoquinoline WYETH CORP (US) 2006-04-19 CN claimed
EP-1291353-B1 6-O-substituted ketolides having antibacterial activity ABBOTT LAB (US) 2005-06-01 EP claimed
EP-1291353-A1 6-O-substituted ketolides having antibacterial activity ABBOTT LABORATORIES (US) 2003-03-12 EP claimed
EP-1007530-A1 6-O-SUBSTITUTED ERYTHROMYCIN COMPOUNDS AND METHOD FOR MAKING SAME ABBOTT LABORATORIES (US) 2000-06-14 EP claimed
US-6028181-A 6-0-Substituted antibacterial erythromycin ketolides and methods of making ABBOTT LABORATORIES (US) 2000-02-22 US claimed
EP-0929563-A1 6-O-SUBSTITUTED KETOLIDES HAVING ANTIBACTERIAL ACTIVITY Abbott Laboratories (US) 1999-07-21 EP claimed
EP-0918783-A1 6-O-SUBSTITUTED ERYTHROMYCINS AND METHOD FOR MAKING THEM ABBOTT LABORATORIES (US) 1999-06-02 EP claimed
WO-1998009978-A1 6-O-SUBSTITUTED KETOLIDES HAVING ANTIBACTERIAL ACTIVITY ABBOTT LABORATORIES (US) 1998-03-12 WO claimed
WO-1997042206-A1 6-O-SUBSTITUTED ERYTHROMYCIN COMPOUNDS AND METHOD FOR MAKING SAME ABBOTT LABORATORIES (US) 1997-11-13 WO claimed
WO-1997042204-A1 6-O-SUBSTITUTED ERYTHROMYCINS AND METHOD FOR MAKING THEM ABBOTT LABORATORIES (US) 1997-11-13 WO claimed