Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 8/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28680935 | 0.83 | — | — | |
| SCHEMBL28756364 | 0.78 | CA12 (0.37) | DNM1ALDH1A1TSHR | |
| SCHEMBL4449546 | 0.72 | — | — | |
| SCHEMBL6974386 | 0.70 | — | — | |
| Water SCHEMBL28113127 | 0.69 | CHRM2 (0.59) | CHRM2DNM1MEN1KMT2AALDH1A1 | |
| SCHEMBL1273922 | 0.67 | DNM1 (0.43) | CHRM2DNM1MEN1KMT2AALDH1A1 | |
| SCHEMBL258807 | 0.67 | DNM1 (0.43) | CHRM2DNM1MEN1KMT2AALDH1A1 | |
| SCHEMBL9641435 | 0.65 | DNM1 (0.41) | CHRM2DNM1MEN1KMT2AALDH1A1 | |
| SCHEMBL232231 | 0.65 | — | — | |
| SCHEMBL22808771 | 0.65 | LCK (0.44) | CHRM2DNM1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090112193-A1 | Systems and devices that utilize photolyzable nitric oxide donors | SEARETE LLC, A LIMITED LIABILITY CORPORATION OF THE STATE OF DELAWARE | 2009-04-30 | — | — | US | disclosed |
| EP-1539134-A4 | NITROSATED AND/OR NITROSYLATED CYCLOOXYGENASE-2 SELECTIVE INHIBITORS, COMPOSITIONS AND METHODS OF USE | NITROMED INC (US) | 2007-04-11 | — | — | EP | disclosed |
| EP-1539134-A2 | NITROSATED AND/OR NITROSYLATED CYCLOOXYGENASE-2 SELECTIVE INHIBITORS, COMPOSITIONS AND METHODS OF USE | Nitromed, Inc. (US) | 2005-06-15 | — | — | EP | disclosed |
| WO-2003103602-A2 | NITROSATED AND/OR NITROSYLATED CYCLOOXYGENASE-2 SELECTIVE INHIBITORS, COMPOSITIONS AND METHODS OF USE | NITROMED, INC. (US) | 2003-12-18 | — | — | WO | disclosed |