Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.48 |
| ▸ | PDE2A | O00408 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6174378 | 1.00 | HTT (0.62) | HTTNPC1ALDH1A1KDM4ECYP3A4 | |
| SCHEMBL23000164 | 1.00 | HTT (0.62) | HTTNPC1ALDH1A1KDM4ECYP3A4 | |
| SCHEMBL4322956 | 0.84 | HTT (0.62) | HTTNPC1ALDH1A1KDM4ECYP3A4 | |
| SCHEMBL1617024 | 0.84 | HTT (0.62) | HTTNPC1ALDH1A1KDM4ECYP3A4 | |
| SCHEMBL1615756 | 0.84 | HTT (0.62) | HTTNPC1ALDH1A1KDM4ECYP3A4 | |
| SCHEMBL20791688 | 0.83 | L3MBTL1 (0.53) | ALDH1A1KMT2ALMNA | |
| SCHEMBL20791689 | 0.83 | L3MBTL1 (0.53) | ALDH1A1KMT2ALMNA | |
| SCHEMBL12393640 | 0.82 | HTT (0.60) | HTTNPC1ALDH1A1KDM4ECYP3A4 | |
| SCHEMBL4322952 | 0.82 | HTT (0.60) | HTTNPC1ALDH1A1KDM4ECYP3A4 | |
| SCHEMBL8310592 | 0.82 | HTT (0.60) | HTTNPC1ALDH1A1KDM4ECYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2019093-A1 | UREA TYPE CINNAMIDE DERIVATIVE | Eisai R&D Management Co., Ltd. (JP) | 2009-01-28 | — | — | EP | disclosed |