SCHEMBL4451472

SCHEMBL4451472

C#CCc1ccc(COC(=O)C2C(C=C(Cl)Cl)C2(C)C)o1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 7/20 0.48
TDP1 Q9NUW8 4/20 0.48
ATM Q13315 2/20 0.48
ADRA2A P08913 1/20 0.48
CNR1 P21554 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
TSHR P16473 3/20 0.43
CYP1A2 P05177 2/20 0.41
CYP2C19 P33261 2/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C9 P11712 1/20 0.41
KMT2A Q03164 5/20 0.40
MEN1 O00255 4/20 0.40
ALDH1A1 P00352 3/20 0.36
HTT P42858 4/20 0.34
MAPT P10636 2/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
POLB P06746 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8822206 0.91 LMNA (0.50) LMNATDP1ATMADRA2ACNR1
SCHEMBL7924295 0.91 LMNA (0.50) LMNATDP1ATMADRA2ACNR1
SCHEMBL11793445 0.87 TDP1 (0.39) LMNATDP1ATMADRA2ACNR1
SCHEMBL9406964 0.86 TDP1 (0.41) LMNATDP1ATMADRA2ACNR1
SCHEMBL12235784 0.84 TDP1 (0.37) LMNATDP1ATMADRA2ACNR1
SCHEMBL2520088 0.84 TDP1 (0.37) LMNATDP1ATMADRA2ACNR1
SCHEMBL12212701 0.84 TDP1 (0.37) LMNATDP1ATMADRA2ACNR1
SCHEMBL8089069 0.84 TDP1 (0.33) LMNATDP1ATMADRA2ACNR1
SCHEMBL8090306 0.84 TDP1 (0.33) LMNATDP1ATMADRA2ACNR1
SCHEMBL8090373 0.81 CA12 (0.32) LMNATDP1ATMADRA2ACNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170156334-A1 INSECTICIDAL AND MITICIDAL MIXTURES OF BIFENTHRIN AND CYANO-PYRETHROIDS FMC CORP (US) 2017-06-08 US disclosed
US-9596857-B2 Insecticidal and miticidal mixtures of bifenthrin and cyano-pyrethroids FMC CORPORATION (US) 2017-03-21 US disclosed
US-9107416-B2 Insecticidal and miticidal mixtures of bifenthrin and cyano-pyrethroids FMC CORPORATION (US) 2015-08-18 US disclosed
US-20150189874-A1 Insecticidal and Miticidal Mixtures of Bifenthrin and Cyano-Pyrethroids FMC CORPORATION (US) 2015-07-09 US disclosed
US-20090131518-A1 Insecticidal and Miticidal Mixtures of Bifenthrin and Cyano-Pyrethroids FMC CORPORATION (US) 2009-05-21 US disclosed
EP-1962592-A2 INSECTICIDAL AND MITICIDAL MIXTURES OF BIFENTHRIN AND CYANO-PYRETHROIDS FMC CORPORATION (US) 2008-09-03 EP disclosed
WO-2007076028-A2 INSECTICIDAL AND MITICIDAL MIXTURES OF BIFENTHRIN AND CYANO-PYRETHROIDS FMC CORPORATION (US) 2007-07-05 WO disclosed
US-5091183-A Mixture of 2-methyl-4-oxo-3-(2-propynyl)cyclopent-2-enyl chrysanthemate and a phenoxybenzyl ester compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-02-25 US disclosed
US-4113968-A FROM A 1-HALO-3-ALKENE-2-OL KURARAY CO., LTD. (JP) 1978-09-12 US disclosed