Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 6/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | CES2 | O00748 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.42 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA4 | P22748 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28993126 | 0.81 | CYP1A2 (0.54) | CES1CYP1A2SRCTSHRCES2 | |
| SCHEMBL2981609 | 0.80 | CES1 (0.52) | CES1CYP1A2SRCTSHRCES2 | |
| SCHEMBL71911 | 0.79 | CYP1A2 (0.62) | CES1CYP1A2TSHRALDH1A1HIF1A | |
| SCHEMBL29614400 | 0.79 | CYP1A2 (0.62) | CES1CYP1A2TSHRALDH1A1HIF1A | |
| SCHEMBL1922803 | 0.79 | CYP1A2 (0.62) | CES1CYP1A2TSHRALDH1A1HIF1A | |
| SCHEMBL14645587 | 0.79 | CES1 (0.56) | CES1CYP1A2SRCTSHRCES2 | |
| SCHEMBL8445440 | 0.79 | CES1 (0.56) | CES1CYP1A2SRCTSHRCES2 | |
| SCHEMBL669851 | 0.79 | CES1 (0.61) | CES1SRCTSHRCES2ALDH1A1 | |
| SCHEMBL6765146 | 0.78 | CES1 (0.45) | CES1CYP1A2SRCTSHRCES2 | |
| SCHEMBL6765147 | 0.78 | CYP1A2 (0.45) | CES1CYP1A2TSHRHIF1AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 956 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109666138-A | A kind of preparation method of fatty poly-ester carbonate | 中国科学院长春应用化学研究所 | 2019-04-23 | — | — | CN | claimed |
| CN-106279046-A | A kind of acetyl hydrazone compounds and preparation method thereof | 六盘水师范学院 | 2017-01-04 | — | — | CN | claimed |
| CN-105503774-A | Preparation method of tianeptine sodium intermediate | JINAN CHENGHUI SHUANGDA CHEMICAL CO LTD | 2016-04-20 | — | — | CN | claimed |
| US-8415312-B2 | Compound which is a nystatin derivative | BIOSERGEN AS (NO) | 2013-04-09 | — | — | US | claimed |
| US-20090074746-A1 | Compounds to treat alzheimer's disease | ALZHEIMER'S COLLABORATION | 2009-03-19 | — | — | US | claimed |
| EP-1951723-A1 | THE APPLICATION USING NON-COVALENT BOND BETWEEN A CUCURBITURIL DERIVATIVE AND A LIGAND | Postech Academy-Industry Foundation (KR) | 2008-08-06 | — | — | EP | claimed |
| US-20070213407-A1 | Compounds to treat Alzheimer's disease | ELAN PHARMACEUTICALS AND PHARMACIA & UPJOHN COMPANY LLC | 2007-09-13 | — | — | US | claimed |
| US-7214715-B2 | Compounds to treat Alzheimer's disease | PHARMACIA & UPJOHN (US) | 2007-05-08 | — | — | US | claimed |
| WO-2007046575-A1 | THE APPLICATION USING NON-COVALENT BOND BETWEEN A CUCURBITURIL DERIVATIVE AND A LIGAND | POSTECH ACADEMY-INDUSTRY FOUNDATION (KR) | 2007-04-26 | — | — | WO | claimed |
| EP-1666452-A2 | Compounds to treat Alzheimer's disease | Elan Pharmaceuticals, Inc. (US) | 2006-06-07 | — | — | EP | claimed |
| WO-2002002505-A2 | COMPOUNDS TO TREAT ALZHEIMER'S DISEASE | ELAN PHARMACEUTICALS, INC. (US) | 2002-01-10 | — | — | WO | claimed |
| WO-2002002520-A2 | COMPOUNDS TO TREAT ALZHEIMER'S DISEASE | ELAN PHARMACEUTICALS, INC. (US) | 2002-01-10 | — | — | WO | claimed |
| WO-2002002518-A2 | COMPOUNDS TO TREAT ALZHEIMER'S DISEASE | ELAN PHARMACEUTICALS, INC. (US) | 2002-01-10 | — | — | WO | claimed |
| EP-0788314-B1 | NONDIGESTIBLE FAT COMPOSITIONS CONTAINING DIVERSELY ESTERIFIED POLYOL POLYESTERS FOR PASSIVE OIL LOSS CONTROL | PROCTER & GAMBLE (US) | 2001-09-12 | — | — | EP | claimed |
| US-6090965-A | Removal of dissolved silicates from alcohol-silicon direct synthesis solvents | OSI SPECIALTIES, INC. (US) | 2000-07-18 | — | — | US | claimed |
| EP-0947521-A2 | Removal of dissolved silicates from alcohol-silicon direct synthesis solvents | WITCO CORPORATION (US) | 1999-10-06 | — | — | EP | claimed |
| EP-0788314-A1 | NONDIGESTIBLE FAT COMPOSITIONS CONTAINING DIVERSELY ESTERIFIED POLYOL POLYESTERS FOR PASSIVE OIL LOSS CONTROL | THE PROCTER & GAMBLE COMPANY (US) | 1997-08-13 | — | — | EP | claimed |
| US-5480667-A | CONTAING NONDIGESTIBLE SOLID POLYOL ESTERS OF SPECIFIED CARBON CHAIN LENGTH FATTY ACID DISPERSED IN LIQUID NONDIGESTIBLE OIL; POTATO CHIPS | CORRIGAN PATRICK J (US) | 1996-01-02 | — | — | US | claimed |
| WO-1994009639-A1 | NONDIGESTIBLE FAT COMPOSITIONS CONTAINING DIVERSELY ESTERIFIED POLYOL POLYESTERS FOR PASSIVE OIL LOSS CONTROL | THE PROCTER & GAMBLE COMPANY (US) | 1994-05-11 | — | — | WO | claimed |
| US-4561493-A | Heat-storing apparatus | HITACHI, LTD. (JP) | 1985-12-31 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070213407-A1 | Compounds to treat Alzheimer's disease | PSEN2, PSEN1, CHAT | CES1 1671/4885CYP1A2 823/4885SRC 3440/4885 |
| US-20090074746-A1 | Compounds to treat alzheimer's disease | PSEN2, PSEN1, CHAT | CES1 1671/4885CYP1A2 823/4885SRC 3440/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.