SCHEMBL6765146

SCHEMBL6765146

O=C(c1ccccc1)C(O)(Cl)c1c(Cl)c(Cl)c(Cl)c(Cl)c1Cl

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES1 P23141 6/20 0.45
SRC P12931 1/20 0.42
CES2 O00748 3/20 0.39
ALDH1A1 P00352 4/20 0.38
TSHR P16473 2/20 0.38
DAO P14920 1/20 0.38
NAPRT Q6XQN6 1/20 0.38
MAPK1 P28482 3/20 0.36
TRPA1 O75762 1/20 0.36
GSK3B P49841 1/20 0.36
HIF1A Q16665 1/20 0.36
CYP1A2 P05177 1/20 0.36
TDP1 Q9NUW8 3/20 0.35
CYP3A4 P08684 2/20 0.35
MAPT P10636 2/20 0.35
CA2 P00918 2/20 0.35
CA4 P22748 2/20 0.35
POLB P06746 1/20 0.35
PARP1 P09874 1/20 0.35
CYP2C19 P33261 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL44516 0.78 CES1 (0.50) CES1SRCCES2ALDH1A1TSHR
SCHEMBL8445440 0.74 CES1 (0.56) CES1SRCCES2ALDH1A1TSHR
SCHEMBL14645587 0.74 CES1 (0.56) CES1SRCCES2ALDH1A1TSHR
SCHEMBL669851 0.74 CES1 (0.61) CES1SRCCES2ALDH1A1TSHR
SCHEMBL11183801 0.72 CES1 (0.58) CES1SRCCES2ALDH1A1TSHR
Water SCHEMBL2479676 0.72 CES1 (0.58) CES1SRCCES2ALDH1A1TSHR
SCHEMBL132067 0.72 CES1 (0.58) CES1SRCCES2ALDH1A1TSHR
SCHEMBL6050014 0.71 CES1 (0.52) CES1SRCCES2ALDH1A1TSHR
SCHEMBL1874832 0.70 CES1 (0.56) CES1SRCCES2ALDH1A1TSHR
SCHEMBL1433235 0.70 CES1 (0.56) CES1SRCCES2ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2892343-A1 USE OF SUBSTITUTED 2,3-DIHYDRO-1-BENZOFURAN-4-CARBOXYLIC ACIDS OR SALTS THEREOF AS ACTIVE SUBSTANCES AGAINST ABIOTIC PLANT STRESS Bayer CropScience AG (DE) 2015-07-15 EP disclosed
WO-2014037349-A1 USE OF SUBSTITUTED 2,3-DIHYDRO-1-BENZOFURAN-4-CARBOXYLIC ACIDS OR SALTS THEREOF AS ACTIVE SUBSTANCES AGAINST ABIOTIC PLANT STRESS BAYER CROPSCIENCE AG (DE) 2014-03-13 WO disclosed
US-20040033380-A1 Process for the manufacture of thermoplastic shrink films SYFAN SAAD (99) LTD. (IL) 2004-02-19 US disclosed
EP-1355976-A1 IMPROVED PROCESS FOR THE MANUFACTURE OF THERMOPLASTIC SHRINK FILMS Syfan Saad (99) Ltd. (IL) 2003-10-29 EP disclosed
WO-2002051913-A1 IMPROVED PROCESS FOR THE MANUFACTURE OF THERMOPLASTIC SHRINK FILMS SYFAN SAAD (99) LTD. (IL) 2002-07-04 WO disclosed