SCHEMBL44518

SCHEMBL44518

NC[C]=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28112235 0.95
SCHEMBL51843 0.67
Ethylenediamine SCHEMBL27891301 0.67
SCHEMBL3895041 0.65
SCHEMBL10982184 0.63
SCHEMBL1388025 0.59
SCHEMBL13735969 0.59
SCHEMBL20637 0.59
SCHEMBL5908 0.59
SCHEMBL44897 0.59

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4156 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114644581-B Amino acid containing aryl thiophenol or aryl selenol modified, recombinant protein, and biosynthesis method and application thereof 北京惠大生物科技有限公司 2024-07-16 CN claimed
WO-2024126869-A1 BENZOXAZINE ACETAL DERIVATIVES FOR PRODUCTION OF RECYCLABLE POLYMERS Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung eingetragener Verein (DE) 2024-06-20 WO claimed
WO-2024125627-A1 CAMPTOTHECIN COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF 上海齐鲁制药研究中心有限公司 2024-06-20 WO claimed
CN-117323294-B Drug-loaded embolism microsphere and preparation method and application thereof 至微(深圳)医学科技有限公司 2024-05-31 CN claimed
CN-117886745-A Preventive medicine for Legionella related diseases and application thereof 青岛国际旅行卫生保健中心(青岛海关口岸门诊部) 2024-04-16 CN claimed
CN-117794923-A Benzodioxane compound, and preparation method and application thereof 南京红云生物科技有限公司 2024-03-29 CN claimed
CN-114507181-B Propionic acid compound containing 5-substituted tetrahydroisoquinoline, pharmaceutical composition and application thereof 中国医学科学院药物研究所 2024-03-26 CN claimed
CN-117736177-A Propionic acid compound containing (R) -5-substituted tetrahydroisoquinoline, preparation method and medical application thereof 中国医学科学院药物研究所 2024-03-22 CN claimed
WO-2024049400-A1 ACID DEGRADABLE SOLID LIPID NANOPARTICLES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-03-07 WO claimed
EP-3921319-B1 IMIDAZO [2, 1-F] [1, 2, 4] TRIAZIN-4-AMINE DERIVATIVES AS TLR7 AGONIST BEIGENE LTD (KY) 2024-03-06 EP claimed
US-4315006-A Benzoxocin derivatives having anxiolytic and anti-convulsant activities GLAXO GROUP LIMITED (GB) 1982-02-09 US claimed
EP-0044142-A1 Process for the preparation of beta-lactam antibiotics BEECHAM GROUP PLC (GB) 1982-01-20 EP claimed
EP-0042299-A1 Benzopyrans, their production and pharmaceutical compositions containing them KOWA COMPANY, LTD. (JP) 1981-12-23 EP claimed
EP-0024843-A1 3,4,5,6-Tetrahydro-2,6-methano-4 beta-amino-1-benzoxocin derivatives, process for their preparation and compositions containing them GLAXO GROUP LIMITED (GB) 1981-03-11 EP claimed
US-4232030-A ANTIBIOTICS MERCK & CO., INC. (US) 1980-11-04 US claimed
US-4226870-A ANTIBIOTICS, BACTERICIDES MERCK & CO., INC. (US) 1980-10-07 US claimed
US-4150145-A ANTIBIOTIC, BACTERICIDES MERCK & CO., INC. (US) 1979-04-17 US claimed
EP-0001265-A1 O-, N- and carboxyl derivatives of thienamycin sulfoxide and sulfone, their preparation and pharmaceuticals containing said compounds MERCK & CO. INC. (US) 1979-04-04 EP claimed
EP-0001264-A1 Substituted N-methylene derivatives of thienamycin sulfoxide and sulfone and their preparation MERCK & CO. INC. (US) 1979-04-04 EP claimed
US-4048107-A Polyurethane foam preparation using amio acetal catalyst OLIN CORPORATION (US) 1977-09-13 US claimed