SCHEMBL51843

SCHEMBL51843

NCC[C]=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL60496 0.77
SCHEMBL97689 0.74
SCHEMBL8812186 0.72 DNM1 (0.50)
SCHEMBL666946 0.72 DNM1 (0.50)
SCHEMBL186389 0.72
SCHEMBL8811124 0.72 DNM1 (0.50)
SCHEMBL381495 0.72 DNM1 (0.50)
SCHEMBL8812602 0.72 DNM1 (0.50)
SCHEMBL465588 0.72 DNM1 (0.50)
SCHEMBL98073 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1512 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118354781-A Peptide inhibitors of interleukin-23 receptor 西兰制药公司 2024-07-16 CN claimed
WO-2024125627-A1 CAMPTOTHECIN COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF 上海齐鲁制药研究中心有限公司 2024-06-20 WO claimed
CN-110691788-B Long acting GIP peptide analogues 哥本哈根大学 2024-05-31 CN claimed
CN-117881415-A Treatment of obesity and obesity-related disorders 安泰博医药 2024-04-12 CN claimed
CN-114507181-B Propionic acid compound containing 5-substituted tetrahydroisoquinoline, pharmaceutical composition and application thereof 中国医学科学院药物研究所 2024-03-26 CN claimed
CN-117736177-A Propionic acid compound containing (R) -5-substituted tetrahydroisoquinoline, preparation method and medical application thereof 中国医学科学院药物研究所 2024-03-22 CN claimed
EP-3442594-B1 BLOCK COPOLYMER FOR OVERCOMING DRUG RESISTANCE OF TUMOURS TO CHEMOTHERAPY, ITS POLYMER-DRUG CONJUGATE, PHARMACEUTICAL COMPOSITION CONTAINING THEM, METHOD OF PREPARATION AND USE THEREOF USTAV MAKROMOLEKULARNI CHEMIE AV CR V V I (CZ) 2024-02-07 EP claimed
US-20230203558-A1 DIAGNOSTIC PEPTIDE FOR USE IN A METHOD OF DIAGNOSIS OF VIRAL INFECTION, KIT AND SYSTEM ORIGINAL G B.V. (NL) 2023-06-29 US claimed
WO-2023099669-A1 PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR ZEALAND PHARMA A/S (DK) 2023-06-08 WO claimed
EP-4127206-A1 DIAGNOSTIC PEPTIDE FOR USE IN A METHOD OF DIAGNOSIS OF VIRAL INFECTION, KIT AND SYSTEM Original G B.V. (NL) 2023-02-08 EP claimed
US-4439360-A Retro-inverso analogues of C-terminal penta and hexapeptides of Substance P ANIC S.P.A. (IT) 1984-03-27 US claimed
US-4424230-A CARBAPENICILLIN ANTIBIOTICS MERCK & CO., INC. (US) 1984-01-03 US claimed
EP-0082568-A2 Retro-inverso analogues of C-terminal penta and hexapeptides of substance P. ANIC S.p.A. (IT) 1983-06-29 EP claimed
US-4335111-A BACTERICIDES AGENCE NATIONAL DE VALORISATION DE LA RECHERCHE (ANVAR) (FR) 1982-06-15 US claimed
US-4277394-A ANALGESICS, ANTIDIARRHEA, TREATMENT OF MENTAL DISEASE TAKEDA CHEMICAL INDUSTRIES, LTD (JP) 1981-07-07 US claimed
US-4232030-A ANTIBIOTICS MERCK & CO., INC. (US) 1980-11-04 US claimed
US-4226870-A ANTIBIOTICS, BACTERICIDES MERCK & CO., INC. (US) 1980-10-07 US claimed
US-4164571-A Medicament which antagonizes the action of gastrin and related polypeptides COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 1979-08-14 US claimed
EP-0001264-A1 Substituted N-methylene derivatives of thienamycin sulfoxide and sulfone and their preparation MERCK & CO. INC. (US) 1979-04-04 EP claimed
EP-0001265-A1 O-, N- and carboxyl derivatives of thienamycin sulfoxide and sulfone, their preparation and pharmaceuticals containing said compounds MERCK & CO. INC. (US) 1979-04-04 EP claimed