Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | IAPP | P10997 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4451959 | 1.00 | ALDH1A1 (0.39) | ALDH1A1TSHRTDP1TRPA1IAPP | |
| SCHEMBL11051211 | 0.83 | ALDH1A1 (0.40) | ALDH1A1TSHRTDP1TRPA1IAPP | |
| SCHEMBL5085205 | 0.83 | ALDH1A1 (0.37) | ALDH1A1TSHRTDP1ALOX15RECQL | |
| SCHEMBL4446486 | 0.83 | ALDH1A1 (0.37) | ALDH1A1TSHRTDP1ALOX15RECQL | |
| SCHEMBL11051216 | 0.83 | ALDH1A1 (0.40) | ALDH1A1TSHRTDP1TRPA1IAPP | |
| SCHEMBL4446487 | 0.83 | ALDH1A1 (0.37) | ALDH1A1TSHRTDP1ALOX15RECQL | |
| SCHEMBL2861207 | 0.78 | NR1I2 (0.61) | ALDH1A1TRPA1ALOX15NR1I2LMNA | |
| SCHEMBL2861204 | 0.78 | NR1I2 (0.61) | ALDH1A1TRPA1ALOX15NR1I2LMNA | |
| SCHEMBL4227977 | 0.77 | NR1I2 (0.34) | NR1I2LMNAPGR | |
| SCHEMBL4227982 | 0.77 | NR1I2 (0.34) | NR1I2LMNAPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2109597-A1 | PROCESS FOR PREPARING DIENONES | DSM IP Assets B.V. (NL) | 2009-10-21 | — | — | EP | claimed |
| WO-2008092655-A1 | PROCESS FOR PREPARING DIENONES | DSM IP ASSETS B.V. (NL) | 2008-08-07 | — | — | WO | claimed |
| EP-2109597-A1 | PROCESS FOR PREPARING DIENONES | DSM IP Assets B.V. (NL) | 2009-10-21 | — | — | EP | disclosed |
| WO-2008092655-A1 | PROCESS FOR PREPARING DIENONES | DSM IP ASSETS B.V. (NL) | 2008-08-07 | — | — | WO | disclosed |