SCHEMBL4452083

SCHEMBL4452083

C[PH](Oc1ccccc1)(Oc1ccccc1)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CA4 P22748 1/20 0.42
LTA4H P09960 5/20 0.39
TSHR P16473 1/20 0.39
KCNA3 P22001 1/20 0.33
CA5A P35218 1/20 0.32
CA5B Q9Y2D0 1/20 0.32
HTR1B P28222 2/20 0.31
LMNA P02545 1/20 0.31
HTR1D P28221 1/20 0.31
NR1H2 P55055 1/20 0.31
BAX Q07812 1/20 0.31
MAOA P21397 1/20 0.31
TAAR1 Q96RJ0 1/20 0.30
ALDH1A1 P00352 1/20 0.30
RECQL P46063 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA9 Q16790 1/20 0.30
SRC P12931 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4449123 0.80 CA4 (0.42) CA4LTA4HTSHRKCNA3CA5A
SCHEMBL16708531 0.76 CA4 (0.48) CA4LTA4HTSHRKCNA3CA5A
SCHEMBL16450272 0.76 CA4 (0.48) CA4LTA4HTSHRKCNA3CA5A
SCHEMBL3138453 0.76 CA4 (0.48) CA4LTA4HTSHRKCNA3CA5A
Bromide SCHEMBL25196436 0.74 CA4 (0.46) CA4LTA4HTSHRKCNA3CA5A
SCHEMBL4451857 0.74 CA4 (0.39) CA4LTA4HTSHRLMNAALDH1A1
SCHEMBL6676063 0.74 LTA4H (0.43) CA4LTA4HTSHRKCNA3CA5A
SCHEMBL7774760 0.74 LTA4H (0.43) CA4LTA4HTSHRKCNA3CA5A
SCHEMBL10976816 0.74 LTA4H (0.43) CA4LTA4HTSHRKCNA3CA5A
Iodide SCHEMBL3408284 0.74 CA4 (0.46) CA4LTA4HTSHRKCNA3CA5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7612148-B2 Hydrogenation catalyst composition and method for hydrogenation of conjugated diene polymer TSRC CORPORATION (TW) 2009-11-03 US disclosed
US-20080146733-A1 Hydrogenation catalyst composition and method for hydrogenation of conjugated diene polymer TSRC CORPORATION (TW) 2008-06-19 US disclosed